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Condition-specific promoter activities in Saccharomyces cerevisiae
Abstract Background Saccharomyces cerevisiae is widely studied for production of biofuels and biochemicals. To improve production efficiency under industrially relevant... -
Acute kidney injury prediction in cardiac surgery patients by a urinary pepti...
Abstract Background Acute kidney injury (AKI) is a prominent problem in hospitalized patients and associated with increased morbidity and mortality. Clinical medicine is... -
Dimethyl fumarate attenuates reactive microglia and long-term memory deficits...
Abstract Background Systemic inflammation is associated with increased cognitive decline and risk for Alzheimer’s disease. Microglia (MG) activated during systemic inflammation... -
iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated d...
Abstract Background Previous research indicated that nitric oxide synthase (NOS) is the key molecule for S-nitrosylation of ryanodine receptor 1 (RyR1) in DMD model mice (mdx... -
Progesterone ameliorates diabetic nephropathy in streptozotocin-induced diabe...
Abstract Background Previous studies reported that 17β-estradiol may influence the progression of diabetic renal disease in females. The present study was intended to provide an... -
MiR-1-3p that correlates with left ventricular function of HCM can serve as a...
Abstract Background MicroRNAs (miRNAs) are non-coding RNAs that function as regulators of gene expression and thereby contribute to the complex disease phenotypes. Hypertrophic... -
Effect of treatment with a JAK2-selective inhibitor, fedratinib, on bone marr...
Abstract Background Progressive bone marrow fibrosis (BMF) is a cardinal feature of many myeloproliferative neoplasms (MPNs) and there is a documented association between the... -
Antioxidant and Antiapoptotic effect of aqueous extract of Pueraria tuberosa ...
Abstract Background Oxidative stress and renal apoptosis play a significant role in the progression of diabetic nephropathy. The tubers of Pueraria tuberosa (Roxb. ex Willd.)... -
Characterization of a strong and constitutive promoter from the Arabidopsis s...
Abstract Background Transgenic technology has become an important technique for crop genetic improvement. The application of well-characterized promoters is essential for... -
TSS seq based core promoter architecture in blood feeding Tsetse fly (Glossin...
Abstract Background Transcription initiation regulation is mediated by sequence-specific interactions between DNA-binding proteins (transcription factors) and cis-elements,... -
Guiding electron orbits with chirped light
We demonstrate that chirped light is effective in shrinking or expanding a class of nonspreading electron eigenstate wave packets in Rydberg atoms. -
Association of adipokines with blood pressure, arterial elasticity and cardia...
Abstract Background Adipokines are a set of cytokines secreted by white adipose tissue that have been suggested to be involved in the development of cardiovascular diseases. We... -
Urinary chitinase 3-like protein 1 for early diagnosis of acute kidney injury...
Abstract Background Acute kidney injury (AKI) occurs frequently and adversely affects patient and kidney outcomes, especially when its severity increases from stage 1 to stages... -
North American experience with Low protein diet for Non-dialysis-dependent ch...
Abstract Whereas in many parts of the world a low protein diet (LPD, 0.6-0.8 g/kg/day) is routinely prescribed for the management of patients with non-dialysis-dependent chronic... -
Inhibition of Salmonella Typhimurium adhesion, invasion, and intracellular su...
Abstract Salmonella enterica serovar Typhimurium infects intestinal epithelia and macrophages, which is prevented by inhibiting adhesion and cell invasion. This study aimed to... -
Multiphoton in vivo imaging with a femtosecond semiconductor disk laser
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped... -
Performance of cytokine models in predicting SLE activity
Abstract Background Identification of universal biomarkers to predict systemic lupus erythematosus (SLE) flares is challenging due to the heterogeneity of the disease. Several... -
Knockout of interleukin-17A protects against sepsis-associated acute kidney i...
Abstract Background Sepsis-associated acute kidney injury (SA-AKI) is an independent risk factor for death in patients with sepsis, but treatment for it is limited. To improve... -
Urinary proteomics for prediction of mortality in patients with type 2 diabet...
Abstract Background The urinary proteomic classifier CKD273 has shown promise for prediction of progressive diabetic nephropathy (DN). Whether it is also a determinant of... -
Association of serum high-density lipoprotein cholesterol with microalbuminur...
Abstract Background The association of serum high-density lipoprotein cholesterol (HDL-C) with microalbuminuria in type 2 diabetes mellitus (T2DM) remains controversial....
