-
A novel transcription factor specifically regulates GH11 xylanase genes in Tr...
Abstract Background The filamentous fungus Trichoderma reesei is widely utilized in industry for cellulase production, but its xylanase activity must be improved to enhance the... -
Module and individual domain deletions of NRPS to produce plipastatin derivat...
Abstract Background Plipastatin, an antifungal lipopeptide, is synthesized by a non-ribosomal peptide synthetase (NRPS) in Bacillus subtilis. However, little information is... -
Systematic design of separation process for bioethanol production from corn s...
Abstract Separation process is very crucial in bioethanol production as it consumes the highest energy in the process. Unlike other works, this research systematically designed... -
Ambiguity of non-systematic chemical identifiers within and between small-mol...
Abstract Background A wide range of chemical compound databases are currently available for pharmaceutical research. To retrieve compound information, including structures,... -
Novel three-dimensional bone ‘mapping’ software can help assess progression o...
Abstract Imaging of bone metastasis response to therapy is a research priority. Stradwin is a new software-tool, with demonstrated sub-voxel accuracy in assessing cortical bone... -
Early-life exposure to three size-fractionated ultrafine and fine atmospheric...
Abstract Background Epidemiological studies have suggested that elevated levels of air pollution contribute to an increased incidence or severity of asthma. Although late-onset... -
Aberrant activation of NF-κB signaling in mammary epithelium leads to abnorma...
Abstract Background Approximately 1 in 5 women diagnosed with breast cancer are considered to have in situ disease, most often termed ductal carcinoma in situ (DCIS). Though... -
The putative β-glucosidase BGL3I regulates cellulase induction in Trichoderma...
Abstract Background The filamentous fungus Trichoderma reesei (anamorph of Hypocrea jecorina) displays increased cellulase expression while growing on inducers such as lactose... -
Fecal metatranscriptomics of macaques with idiopathic chronic diarrhea reveal...
Abstract Background Idiopathic chronic diarrhea (ICD) is a common cause of morbidity and mortality among juvenile rhesus macaques. Characterized by chronic inflammation of the... -
Major differential gene regulation in Coxiella burnetii between in vivo and i...
Abstract Background Coxiella burnetii is the causative agent of the zoonotic disease Q fever. As it is an intracellular pathogen, infection by C. burnetii requires adaptation to... -
Prediction of advanced colonic neoplasm in symptomatic patients: a scoring sy...
Abstract Background Fast-track colonoscopy to detect patients with colorectal cancer based on high-risk symptoms is associated with low sensitivity and specificity. The aim was... -
Pancreatic cancer-initiating cell exosome message transfer into noncancer-ini...
Abstract Background Cancer-initiating cell (CIC) exosomes (CIC-TEX) are suggested reprogramming Non-CIC. Mode of message transfer and engagement of CIC-markers being disputed,... -
Reference genome and comparative genome analysis for the WHO reference strain...
The BCG live attenuated TB vaccine is one of the oldest and most widely used vaccines in human medicine. Each year, BCG vaccines are administered to over 100 million newborns... -
Construction of a trifunctional cellulase and expression in Saccharomyces cer...
Abstract Background Cellulose is the most important component of lignocellulose, and its degradation requires three different types of enzymes to act synergistically. There have... -
A toolset of constitutive promoters for metabolic engineering of Rhodosporidi...
Abstract Background Rhodosporidium toruloides is a promising host for the production of bioproducts from lignocellulosic biomass. A key prerequisite for efficient pathway... -
Suppression of endothelial cell migration by tumor associated macrophage-deri...
Abstract Objective To study the mechanism by which epithelial ovarian cancer (EOC)-derived exosomes restore the migration of endothelial cells that is suppressed by TAM-derived... -
Optimization of cellulolytic enzyme components through engineering Trichoderm...
Abstract Background Cellulolytic enzymes produced by Trichoderma reesei are widely studied for biomass bioconversion, and enzymatic components vary depending on different... -
Biological representation of chemicals using latent target interaction profile
Abstract Background Computational prediction of a phenotypic response upon the chemical perturbation on a biological system plays an important role in drug discovery, and many... -
Improving squalene production by enhancing the NADPH/NADP+ ratio, modifying t...
Abstract Background Squalene is currently used widely in the food, cosmetics, and medicine industries. It could also replace petroleum as a raw material for fuels. Microbial... -
Mass spectrometry-based identification and whole-genome characterisation of t...
Abstract Background The pteropine orthoreovirus (PRV) was isolated from monkey (Macaca fascicularis) faecal samples collected from human-inhabited areas in Lopburi Province,...
