228 items found

Types: other Tags: Biochemistry Biotechnology Physiology Science Policy

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    Dried blood spot versus venous blood sampling for phenylalanine and tyrosine

    Abstract Background This study investigated the agreement between various dried blood spot (DBS) and venous blood sample measurements of phenylalanine and tyrosine...
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    Omalizumab in patients with severe asthma and persistent sputum eosinophilia

    Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who...
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    Additional file 7: of The prominent alteration in transcriptome and metabolom...

    Table S7. The homologous genes between M. bovis BCG and M. tuberculosis H37Rv. (XLS 1840 kb)
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    Lung function reductions associated with motor vehicle density in chronic obs...

    Abstract Background Motor vehicle-related air pollution can potentially impair lung function. The effect of pollution in people with compromised pulmonary function such as in...
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    Lytic polysaccharide monooxygenases and other oxidative enzymes are abundantl...

    Abstract Background Starch is the second most abundant plant-derived biomass and a major feedstock in non-food industrial applications and first generation biofuel production....
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    Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients w...

    Abstract Background Intracellular signaling through cyclic nucleotides, both cyclic AMP and cyclic GMP, is altered in colorectal cancer. Accordingly, it is hypothesized that an...
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    cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GP...

    Abstract Background The glycoprotein (GP) Ib-IX-V complex is a unique platelet plasma membrane receptor, which is essential for platelet adhesion and thrombus formation. GPIbα,...
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    ERα-36 regulates progesterone receptor activity in breast cancer

    Abstract Background Alterations in estrogen and progesterone signaling, via their respective receptors, estrogen receptor alpha (ERα) and progesterone receptor (PR),...
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    Highly active promoters and native secretion signals for protein production d...

    Abstract Background The filamentous ascomycete Aspergillus niger is used in many industrial processes for the production of enzymes and organic acids by batch and fed-batch...
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    Computed tomography-derived area and density of pectoralis muscle associated ...

    Abstract Background Muscle wasting is associated with prognosis in patients with chronic obstructive pulmonary disease (COPD). The cross-sectional area of skeletal muscles on...
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    Bacterial communities and metabolic activity of faecal cultures from equol pr...

    Abstract Background Isoflavones are polyphenols with estrogenic activity found mainly in soy and soy-derived products that need to be metabolised in the intestine by the gut...
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    The effects of green cardamom on blood glucose indices, lipids, inflammatory ...

    Abstract Background The relationship between dietary components and nonalcoholic fatty liver disease (NAFLD) needs to be further investigated. The potential health benefits of...
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    Visualization of guided and leaky wave behaviors in an indium tin oxide metal...

    We explored the use of the optically transparent semiconductor indium tin oxide (ITO) as an alternative to optically opaque metals for the fabrication of photonic structures in...
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    The putative β-glucosidase BGL3I regulates cellulase induction in Trichoderma...

    Abstract Background The filamentous fungus Trichoderma reesei (anamorph of Hypocrea jecorina) displays increased cellulase expression while growing on inducers such as lactose...
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    Levels of CXCL13 and sICAM-1 correlate with disease activity score in patient...

    Abstract Background Tocilizumab (TCZ), a humanized monoclonal antibody against the interleukin-6 receptor, has been proven to be a safe and effective treatment for rheumatoid...
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    Circulating cathelicidin levels correlate with mucosal disease activity in ul...

    Abstract Background Cathelicidin (LL-37) is an antimicrobial peptide known to be associated with various autoimmune diseases. We attempt to determine if cathelicidin can...
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    Contacting out-of-hours primary care or emergency medical services for time-c...

    Abstract Background Out-of-hours (OOH) healthcare services in Western countries are often differentiated into out-of-hours primary healthcare services (OOH-PC) and emergency...
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    Supplement of microbiota-accessible carbohydrates prevents neuroinflammation ...

    Abstract Background Western pattern diets induce neuroinflammation and impair cognitive behavior in humans and animals. Neuroinflammation and cognitive impairment have been...
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    Examining the role of unmeasured confounding in mediation analysis with genet...

    Abstract Background In mediation analysis if unmeasured confounding is present, the estimates for the direct and mediated effects may be over or under estimated. Most methods...
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    Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation...

    Abstract Background Alcohol abuse and alcoholism lead to alcohol liver disease such as alcoholic fatty liver. Parkin is a component of the multiprotein E3 ubiquitin ligase...