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Dried blood spot versus venous blood sampling for phenylalanine and tyrosine
Abstract Background This study investigated the agreement between various dried blood spot (DBS) and venous blood sample measurements of phenylalanine and tyrosine... -
Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
Lung function reductions associated with motor vehicle density in chronic obs...
Abstract Background Motor vehicle-related air pollution can potentially impair lung function. The effect of pollution in people with compromised pulmonary function such as in... -
Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients w...
Abstract Background Intracellular signaling through cyclic nucleotides, both cyclic AMP and cyclic GMP, is altered in colorectal cancer. Accordingly, it is hypothesized that an... -
Computed tomography-derived area and density of pectoralis muscle associated ...
Abstract Background Muscle wasting is associated with prognosis in patients with chronic obstructive pulmonary disease (COPD). The cross-sectional area of skeletal muscles on... -
The effects of green cardamom on blood glucose indices, lipids, inflammatory ...
Abstract Background The relationship between dietary components and nonalcoholic fatty liver disease (NAFLD) needs to be further investigated. The potential health benefits of... -
Visualization of guided and leaky wave behaviors in an indium tin oxide metal...
We explored the use of the optically transparent semiconductor indium tin oxide (ITO) as an alternative to optically opaque metals for the fabrication of photonic structures in... -
The putative β-glucosidase BGL3I regulates cellulase induction in Trichoderma...
Abstract Background The filamentous fungus Trichoderma reesei (anamorph of Hypocrea jecorina) displays increased cellulase expression while growing on inducers such as lactose... -
Circulating cathelicidin levels correlate with mucosal disease activity in ul...
Abstract Background Cathelicidin (LL-37) is an antimicrobial peptide known to be associated with various autoimmune diseases. We attempt to determine if cathelicidin can... -
Contacting out-of-hours primary care or emergency medical services for time-c...
Abstract Background Out-of-hours (OOH) healthcare services in Western countries are often differentiated into out-of-hours primary healthcare services (OOH-PC) and emergency... -
The neuroregenerative effects of topical decorin on the injured mouse cornea
Abstract Background The cornea is innervated with a rich supply of sensory nerves that play important roles in ocular surface health. Any injury or pathology of the corneal... -
Effects of weight change on apolipoprotein B-containing emerging atherosclero...
Abstract Background and aims Non-high-density (HDL)-cholesterol, low-density lipoprotein (LDL)-particle number, apolipoprotein B, lipoprotein(a) (Lp(a)), and small-dense (sdLDL)... -
Multiphoton in vivo imaging with a femtosecond semiconductor disk laser
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped... -
A novel pyruvate kinase and its application in lactic acid production under o...
Abstract Background Pyruvate kinase (Pyk) catalyzes the generation of pyruvate and ATP in glycolysis and functions as a key switch in the regulation of carbon flux distribution.... -
A report on the use of a single intra-articular administration of autologous ...
Abstract Background Osteoarthritis (OA) represents a significant burden to societies, as it affects quality of life, performance and poses a large healthcare cost. We aimed to... -
Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and s...
Abstract Background Cesium-137 (137Cs) is one of the major and most clinically relevant radionuclides of concern in a radiological dispersal device, “dirty bomb” scenario as... -
A novel method for the quantification of fatty infiltration in skeletal muscle
Abstract Background Fatty infiltration of the skeletal muscle is a common but poorly understood feature of many myopathies. It is best described in human muscle, where... -
The index of prediction accuracy: an intuitive measure useful for evaluating ...
Abstract Background Many measures of prediction accuracy have been developed. However, the most popular ones in typical medical outcome prediction settings require additional... -
Identification of non-conserved residues essential for improving the hydrocar...
Abstract Background Cyanobacteria produce hydrocarbons corresponding to diesel fuels by means of aldehyde-deformylating oxygenase (ADO). ADO catalyzes a difficult and unusual... -
Noninvasive label-free imaging of microhemodynamics by optical-resolution pho...
In vivo microcirculatory imaging facilitates the fundamental understanding of many major diseases. However, existing techniques generally require invasive procedures or...
