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Spatial patterns of unemployment in Central Europe: emerging development axes...
In this paper, we focus on mapping and analysing the spatial patterns of unemployment in four Central European countries – Austria, Czechia, Germany, and Poland, on municipal... -
Saturated absorption competition microscopy
Owing to the advantage of being non-invasive in observing living samples, far-field optical microscopy is widely used in the life sciences, but the existence of the diffraction... -
CellTag Indexing: genetic barcode-based sample multiplexing for single-cell g...
Abstract High-throughput single-cell assays increasingly require special consideration in experimental design, sample multiplexing, batch effect removal, and data... -
Buying and selling human eggs: infertility providers’ ethical and other conce...
Abstract Background Egg donor agencies are increasingly being used as part of IVF in the US, but are essentially unregulated, posing critical ethical and policy questions... -
Mobile Technology for Improved Family Planning (MOTIF): the development of a ...
Abstract Background The objective of this paper is to outline the formative research process used to develop the MOTIF mobile phone-based (mHealth) intervention to support... -
"OPTImAL": an ontology for patient adherence modeling in physical activity do...
Abstract Background Maintaining physical fitness is a crucial component of the therapeutic process for patients with cardiovascular disease (CVD). Despite the known importance... -
Organoids of epithelial ovarian cancer as an emerging preclinical in vitro to...
Abstract Epithelial ovarian cancer (EOC) remains the most lethal gynecological cancer in developed countries, indicating the need for further research. Although current cancer... -
RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling p...
Abstract Background Runt-related transcription factor 1 (RUNX1) plays the roles of an oncogene and an anti-oncogene in epithelial tumours, and abnormally elevated RUNX1 has been... -
Real-time handheld multispectral optoacoustic imaging
Multispectral optoacoustic tomography (MSOT) of functional and molecular contrast has the potential to find broad deployment in clinical practice. We have developed the first... -
CDC42 controls the activation of primordial follicles by regulating PI3K sign...
Abstract Background In mammalian females, progressive activation of dormant primordial follicles in adulthood is crucial for the maintenance of the reproductive lifespan.... -
Reengineering of MeSH thesauri for term selection to optimize literature retr...
Abstract Background PubMed is a widely used database for scientists to find biomedical-related literature. Due to the complexity of the selected research subject and its... -
Multiphoton in vivo imaging with a femtosecond semiconductor disk laser
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped... -
Novel Indolyl-chalcones Target Stathmin to Induce Cancer Cell Death
Efficacy of current therapies for advanced and metastatic cancers remains a challenge in clinical practice. We investigated the anti-cancer potency of 3 novel indoly-chalcones... -
ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis p...
Abstract Background Transcription factor binding, histone modification, and chromatin accessibility studies are important approaches to understanding the biology of gene... -
Additional file 10: of lncRNA profile of Apis mellifera and its possible role...
The top 20 enriched KEGG pathways of differentially expressed mRNAs from the three comparison groups. (XLS 31 kb) -
Horizontal gene transfer is not a hallmark of the human genome
Abstract Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as... -
In vitro and in silico studies of terpenes, terpenoids and related compounds ...
Abstract Background In order to develop new larvicidal agents derived from phytochemicals, the larvicidal activity of fifty molecules that are constituent of essential oils was... -
A global sensitivity analysis approach for morphogenesis models
Abstract Background Morphogenesis is a developmental process in which cells organize into shapes and patterns. Complex, non-linear and multi-factorial models with images as... -
Volumetric optical mapping in early embryonic hearts using light-sheet micros...
Optical mapping (OM) of electrical activity using voltage-sensitive fluorescent dyes is a powerful tool for the investigation of embryonic cardiac electrophysiology. However,... -
Interventions to develop collectivistic leadership in healthcare settings: a ...
Abstract Background Collective or shared leadership approaches have been associated with team performance outcomes in several sectors. Based on this evidence, there have been...
