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Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
Twenty-five years of optical coherence tomography: the paradigm shift in sens...
Optical coherence tomography (OCT) has become one of the most successful optical technologies implemented in medicine and clinical practice mostly due to the possibility of... -
Data quality and feasibility of the Experience Sampling Method across the spe...
Abstract Background Due to a number of methodological advantages and theoretical considerations, more and more studies in clinical psychology research employ the Experience... -
Changing the Antibiotic Prescribing of general practice registrars: the ChAP ...
Abstract Background Australian General Practitioners (GPs) are generous prescribers of antibiotics, prompting concerns including increasing antimicrobial resistance in the... -
Buying and selling human eggs: infertility providers’ ethical and other conce...
Abstract Background Egg donor agencies are increasingly being used as part of IVF in the US, but are essentially unregulated, posing critical ethical and policy questions... -
GCAC: galaxy workflow system for predictive model building for virtual screening
Abstract Background Traditional drug discovery approaches are time-consuming, tedious and expensive. Identifying a potential drug-like molecule using high throughput screening... -
Andrographis paniculata transcriptome provides molecular insights into tissue...
Abstract Background Kalmegh (Andrographis paniculata) has been widely exploited in traditional medicine for the treatment of infectious diseases and health disorders.... -
Current infection control practices used in Australian and New Zealand cystic...
Abstract Background The 2013 update of the Infection Prevention and Control (IP&C) Guideline outlined recommendations to prevent the spread of CF respiratory pathogens. We... -
Construction and importance of video based analyses teaching in physical educ...
Abstract Introduction Today, Video Based Analysis (VBA) is one of the teaching methods widely used in different fields that help in effective teaching and learning process.... -
Using artificial intelligence to reduce diagnostic workload without compromis...
Abstract Background A substantial proportion of microbiological screening in diagnostic laboratories is due to suspected urinary tract infections (UTIs), yet approximately two... -
A training manual for event history analysis using longitudinal data
Abstract Objective This research note reports on the activities of the Multi-centre Analysis of the Dynamics of Internal Migration And Health (MADIMAH) project aimed at... -
Slot-mode optomechanical crystals: a versatile platform for multimode optomec...
Cavity optomechanical systems are being studied for their potential in areas such as metrology, communications, and quantum information science. For a number of recently... -
Repeat: a framework to assess empirical reproducibility in biomedical research
Abstract Background The reproducibility of research is essential to rigorous science, yet significant concerns of the reliability and verifiability of biomedical research have... -
DNetDB: The human disease network database based on dysfunctional regulation ...
Abstract Disease similarity study provides new insights into disease taxonomy, pathogenesis, which plays a guiding role in diagnosis and treatment. The early studies were... -
The index of prediction accuracy: an intuitive measure useful for evaluating ...
Abstract Background Many measures of prediction accuracy have been developed. However, the most popular ones in typical medical outcome prediction settings require additional... -
Calibration: the Achilles heel of predictive analytics
Abstract Background The assessment of calibration performance of risk prediction models based on regression or more flexible machine learning algorithms receives little... -
IDAAPM: integrated database of ADMET and adverse effects of predictive modeli...
Abstract Background The disposition of a pharmaceutical compound within an organism, i.e. its Absorption, Distribution, Metabolism, Excretion, Toxicity (ADMET) properties and... -
Prevalence and pattern of co-occurring musculoskeletal pain and its associati...
Abstract Background Individuals with persistent low back pain commonly have a broad range of other health concerns including co-occurring musculoskeletal pain, which... -
A simple method for identifying parameter correlations in partially observed ...
Abstract Background Parameter estimation represents one of the most significant challenges in systems biology. This is because biological models commonly contain a large number... -
FORGe: prioritizing variants for graph genomes
Abstract There is growing interest in using genetic variants to augment the reference genome into a graph genome, with alternative sequences, to improve read alignment accuracy...
