-
ISSEC: inferring contacts among protein secondary structure elements using de...
Abstract Background The formation of contacts among protein secondary structure elements (SSEs) is an important step in protein folding as it determines topology of protein... -
Photocontrolled reversible self-assembly of dodecamer nitrilase
Abstract Background Naturally photoswitchable proteins act as a powerful tool for the spatial and temporal control of biological processes by inducing the formation of a... -
Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeuti...
Abstract Background The Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) outbreak originating in Wuhan, China, has raised global health concerns and the... -
A principal components method constrained by elementary flux modes: analysis ...
Abstract Background Non-negative linear combinations of elementary flux modes (EMs) describe all feasible reaction flux distributions for a given metabolic network under the... -
FCMDAP: using miRNA family and cluster information to improve the prediction ...
Abstract Background Biological experiments have confirmed the association between miRNAs and various diseases. However, such experiments are costly and time consuming.... -
GAPPadder: a sensitive approach for closing gaps on draft genomes with short ...
Abstract Background Closing gaps in draft genomes is an important post processing step in genome assembly. It leads to more complete genomes, which benefits downstream genome... -
Inferring miRNA sponge co-regulation of protein-protein interactions in human...
Abstract Background Recent studies have shown that the crosstalk between microRNA (miRNA) sponges plays an important role in human cancers. However, the co-regulation roles of... -
A systemic approach to screening high-throughput RT-qPCR data for a suitable ...
Abstract Background The consensus on how to choose a reference gene for serum or plasma miRNA expression qPCR studies has not been reached and none of the potential candidates... -
Handheld multispectral fluorescence lifetime imaging system for in vivo appli...
There is an increasing interest in the application of fluorescence lifetime imaging (FLIM) for medical diagnosis. Central to the clinical translation of FLIM technology is the... -
bioSyntax: syntax highlighting for computational biology
Abstract Background Computational biology requires the reading and comprehension of biological data files. Plain-text formats such as SAM, VCF, GTF, PDB and FASTA, often contain... -
The effect of dot size in random-dot stereograms on the results of stereoacui...
Abstract Background This study aimed to evaluate the effect of the size of the dots in random-dot stereograms on the results of stereoacuity measurements. Methods A stereopsis... -
All-dielectric metasurface absorbers for uncooled terahertz imaging
Imaging in the terahertz (THz) range of the electromagnetic spectrum is difficult owing to the lack of high-power sources and efficient detectors. For decades, there has been... -
A kinetic metabolic study of lipid production in Chlorella protothecoides und...
Abstract Background Microalgae have been proposed as potential platform to produce lipid-derived products, such as biofuels. Knowledge on the intracellular carbon flow... -
A random effects model for the identification of differential splicing (REIDS...
Abstract Background Alternative gene splicing is a common phenomenon in which a single gene gives rise to multiple transcript isoforms. The process is strictly guided and...
