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Feasibility and evaluation of a large-scale external validation approach for ...
Abstract Background To demonstrate how the Observational Healthcare Data Science and Informatics (OHDSI) collaborative network and standardization can be utilized to scale-up... -
Involving general practice trainees in clinical practice guideline adaptation
Abstract Background It is unclear whether it is feasible to involve residents in guideline development or adaptation. We designed a multifaceted training program that combines... -
Complex microseismic activity and depth-dependent stress field changes in Wak...
Abstract We examined the spatial relationship between seismicity and upper crustal structure in the Wakayama region, northwestern Kii Peninsula, Japan, by investigating... -
INSPECT: extending plane-casting for 6-DOF control
Abstract INSPECT is a novel interaction technique for 3D object manipulation using a rotation-only tracked touch panel. Motivated by the applicability of the technique on... -
Projecting prevalence, costs and evaluating simulated interventions for diabe...
Abstract Background Diabetes-related end stage renal disease (DM-ESRD) is a devastating consequence of the type 2 diabetes epidemic, both of which disproportionately affect... -
BioReader: a text mining tool for performing classification of biomedical lit...
Abstract Background Scientific data and research results are being published at an unprecedented rate. Many database curators and researchers utilize data and information from... -
Multiphoton in vivo imaging with a femtosecond semiconductor disk laser
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped... -
DNetDB: The human disease network database based on dysfunctional regulation ...
Abstract Disease similarity study provides new insights into disease taxonomy, pathogenesis, which plays a guiding role in diagnosis and treatment. The early studies were... -
Millstone: software for multiplex microbial genome analysis and engineering
Abstract Inexpensive DNA sequencing and advances in genome editing have made computational analysis a major rate-limiting step in adaptive laboratory evolution and microbial... -
The French National Registry of patients with Facioscapulohumeral muscular dy...
Abstract Background Facioscapulohumeral muscular dystrophy is a rare inherited neuromuscular disease with an estimated prevalence of 1/20,000 and France therefore harbors about... -
Horizontal gene transfer is not a hallmark of the human genome
Abstract Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as... -
Development and validation of a model for the adoption of structured and stan...
Abstract Background Healthcare professionals provide care to patients and during that process, record large quantities of data in patient records. Data in an Electronic Health... -
Multifocal optical nanoscopy for big data recording at 30 TB capacity and gig...
The onrushing challenge to store the exponentially increasing amount of information generated each year with sustainable big data techniques has compelled ongoing technical... -
Interventions to prevent hemodynamic instability during renal replacement the...
Abstract Background Hemodynamic instability during renal replacement therapy (HIRRT) in the form of intradialytic hypotension (IDH) is a frequent complication of hemodialysis in... -
The application rate for urology specialty compared with other specialties fr...
Abstract Background Reduced clinical exposure to urology at the undergraduate or internship level is the main explanation for the marked decrease in applicants to urology... -
dedup_wf_001--8300687d0c4a1d2ffc91a108992e20a2
Introduction: Understanding and planning for the factors that impact supply cost and unplanned readmission risk for total joint arthroplasty (TJA) patients is helpful for... -
Correction to: Goats in the city: prevalence of Giardia duodenalis and Crypto...
In the original publication of this article [1] the supplementary file was missing two primers for the PCR reaction and the PCR conditions of Giardia and Cryptosporidium. In... -
A step-by-step approach to improve data quality when using commercial busines...
Abstract Background Food environment characterization in health studies often requires data on the location of food stores and restaurants. While commercial business lists are... -
Novel subpopulations in date palm (Phoenix dactylifera) identified by populat...
Abstract Background The date palm is one of the oldest cultivated fruit trees. The tree can withstand high temperatures and low water and the fruit can be stored dry offering... -
A novel joint analysis framework improves identification of differentially ex...
Abstract Motivation Detecting differentially expressed (DE) genes between disease and normal control group is one of the most common analyses in genome-wide transcriptomic data....