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Helios + Regulatory T cell frequencies are correlated with control of viral r...
Abstract Background The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation.... -
Increased calcium intake is associated lower serum 25-hydroxyvitamin D levels...
Abstract Background There are indications that an increased intake of calcium has a vitamin D sparing effect, which might be explained by a decreased catabolism of... -
Serum interleukin-6 is an indicator for severity in 901 patients with SARS-Co...
Abstract Background Interleukin-6 (IL-6) was proposed to be associated with the severity of coronavirus disease 2019 (COVID-19). The present study aimed to explore the kinetics... -
Association of Schistosoma haematobium infection morbidity and severity on co...
Abstract Background Individuals living in Schistosoma haematobium endemic areas are often at risk of having other communicable diseases simultaneously. This usually creates... -
EWS and FUS bind a subset of transcribed genes encoding proteins enriched in ...
Abstract Background FUS (TLS) and EWS (EWSR1) belong to the FET-protein family of RNA and DNA binding proteins. FUS and EWS are structurally and functionally related and... -
Influences of cancer symptom knowledge, beliefs and barriers on cancer sympto...
Abstract Background People from lower socioeconomic groups have worse survival outcomes for cancer, which in part reflects later-stage disease at diagnosis. The mechanisms... -
Production results from piglets vaccinated in a field study in Spain with a T...
Abstract Background PRRS is a viral disease of pigs and sows that is one of the most costly to the pig industry worldwide. The disease can be controlled by focusing on different... -
Burden of pneumocystis pneumonia in HIV-infected adults in sub-Saharan Africa...
Abstract Background Seroprevalence data and clinical studies in children suggest that the burden of pneumocystis pneumonia (PCP) in Africa may be underestimated. We performed a... -
Divergent transcriptomic responses underlying the ranaviruses-amphibian inter...
Abstract Background Ranaviruses (family Iridoviridae, nucleocytoplasmic large DNA viruses) have been reported as promiscuous pathogens of cold-blooded vertebrates. Rana grylio... -
Efficacy of a physical activity programme combining individualized aerobic ex...
Abstract Background In individuals with neuromuscular diseases (NMD), symptoms of muscle weakness, fatigue and pain may limit physical activity. Inactivity leads to reduced... -
Seroprevalence of anti-HBc, risk factors of occupationally acquired HBV infec...
Abstract Background Due to numerous blood exposures hospital staff are at risk of acquiring hepatitis B virus (HBV) infections. This study aimed at estimating prevalence of HBV,... -
A systematic review of BCG vaccination policies among high-risk groups in low...
Abstract Background Bacille Calmette-Guérin (BCG) vaccination against tuberculosis (TB) is widespread in high-TB-burden countries, however, BCG vaccination policies in... -
How much allopurinol does it take to get to target urate? Comparison of actua...
Abstract Objective Allopurinol dosing has frequently been limited based on creatinine clearance (CrCL), resulting in failure to achieve target serum urate (SU). The aim of this... -
Comparison of developmental milestone attainment in early treated HIV-infecte...
Abstract Background Infant HIV infection is associated with delayed milestone attainment. The extent to which effective antiretroviral therapy (ART) prevents these delays is not... -
Prevalence of chronic infections and susceptibility to measles and varicella-...
Abstract Background Large numbers of Latin American immigrants recently arrived in Western Europe. Curative and preventive programmes need to take account of their risk of... -
Prevalence and distribution of soil-transmitted helminth infections in Nigeri...
Abstract Background Soil transmitted helminth (STH) infections still remain a notable health problem in resource-limited countries due to difficulties in the implementation of... -
In vivo analysis of Nef’s role in HIV-1 replication, systemic T cell activati...
Background Nef is a multifunctional HIV-1 protein critical for progression to AIDS. Humans infected with nef(−) HIV-1 have greatly delayed or no disease consequences. We have... -
Effects of prolonged direct hemoperfusion using a polymyxin B immobilized fib...
Abstract Background The aim of this study was to evaluate the effect of prolonged direct hemoperfusion using polymyxin B immobilized fiber cartridges (PMX-DHP) on interleukin-6... -
Varicella zoster virus-associated morbidity and mortality in Africa â a sys...
Abstract Background Varicella zoster virus (VZV) causes varicella and herpes zoster. These vaccine preventable diseases are common globally. Most available data on VZV... -
Investigation of the host transcriptional response to intracellular bacterial...
Abstract Background During infection by intracellular pathogens, a highly complex interplay occurs between the infected cell trying to degrade the invader and the pathogen which...
