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Post-traumatic acute kidney injury: a cross-sectional study of trauma patients
Abstract Background The causes of post-traumatic acute kidney injury (AKI) are multifactorial, and shock associated with major trauma has been proposed to result in inadequate... -
Adherence to guidelines across different specialties to prevent infections in...
Abstract Background Substantial numbers of patients are now receiving either immunosuppressive therapies or chemotherapy. There are significant risks in such patients of... -
Patternable particle microarray utilizing controllable particle delivery
Abstract In this study, we demonstrate an on-demand delivering and sequential arraying of single microparticles utilizing multiple pneumatic pressure-driven elastomer valves and... -
A virtual clinic for the management of diabetes-type 1: study protocol for a ...
Abstract Background Diabetes is a serious chronic disease. Medical treatment and good psychosocial support are needed to cope with acute and long-term effects of diabetes.... -
Central nervous system manganese induced lesions and clinical consequences in...
Abstract Background Around 47–74% of patients with hereditary hemorrhagic telangiectasia (HHT) have hepatic vascular malformations (HVMs); magnetic resonance images (MRI) of the... -
Risk factors for death among children 0–59 months of age with moderate-to-sev...
Abstract Background Despite major improvements in child survival rates, the number of deaths due to diarrhea remains unacceptably high. We aimed to describe diarrhea-associated... -
Epidermal grafting versus split-thickness skin grafting for wound healing (EP...
Abstract Background Split-thickness skin grafting (SSG) is an important modality for wound closure. However, the donor site becomes a second, often painful wound, which may take... -
The impairment of small nerve fibers in severe sepsis and septic shock
Abstract Background A decrease of small nerve fibers in skin biopsies during the course of critical illness has been demonstrated recently. However, the diagnostic use of skin... -
Expression of ACE2 and a viral virulence-regulating factor CCN family member ...
Abstract It has been reported that coronavirus disease 2019 (COVID-19) causes not only pneumonia but also systemic inflammations including central nervous system (CNS)... -
Does left ventricular hypertrophy affect cognition and brain structural integ...
Abstract Background Cognitive impairment is common in type 2 diabetes mellitus, and there is a strong association between type 2 diabetes and Alzheimer’s disease. However, we do... -
Comparison of developmental milestone attainment in early treated HIV-infecte...
Abstract Background Infant HIV infection is associated with delayed milestone attainment. The extent to which effective antiretroviral therapy (ART) prevents these delays is not... -
Single-photon emission computed tomography/computed tomography imaging of RAG...
Abstract Background Expression of the Receptor for Advanced Glycation Endproducts (RAGE) initiates pro-inflammatory pathways resulting in lung destruction. We hypothesized that... -
Examining the role of unmeasured confounding in mediation analysis with genet...
Abstract Background In mediation analysis if unmeasured confounding is present, the estimates for the direct and mediated effects may be over or under estimated. Most methods... -
Involvement of DPP9 in gene fusions in serous ovarian carcinoma
Abstract Background A fusion gene is a hybrid gene consisting of parts from two previously independent genes. Chromosomal rearrangements leading to gene breakage are frequent in... -
TSS seq based core promoter architecture in blood feeding Tsetse fly (Glossin...
Abstract Background Transcription initiation regulation is mediated by sequence-specific interactions between DNA-binding proteins (transcription factors) and cis-elements,... -
Suppression of endothelial cell migration by tumor associated macrophage-deri...
Abstract Objective To study the mechanism by which epithelial ovarian cancer (EOC)-derived exosomes restore the migration of endothelial cells that is suppressed by TAM-derived... -
Investigation of the host transcriptional response to intracellular bacterial...
Abstract Background During infection by intracellular pathogens, a highly complex interplay occurs between the infected cell trying to degrade the invader and the pathogen which... -
Effect of linoleic acid on ischemic heart disease and its risk factors: a Men...
Abstract Background The role of n-6 polyunsaturated fatty acids (PUFAs) in ischemic heart disease (IHD) is controversial, and dietary guidelines vary. Observationally, lower... -
Very low sensitivity of wet mount microscopy compared to PCR against culture ...
Abstract Background Trichomonas vaginalis (TV) causes the Trichomoniasis Syndrome composed of vaginitis in women, urethritis in men and tube infection in both sexes. This... -
Identification of G-quadruplex structures that possess transcriptional regula...
Abstract Background G-quadruplex is a DNA secondary structure that has been shown to play an important role in biological systems. In a previous study, we identified 1998...
