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Post-traumatic acute kidney injury: a cross-sectional study of trauma patients
Abstract Background The causes of post-traumatic acute kidney injury (AKI) are multifactorial, and shock associated with major trauma has been proposed to result in inadequate... -
WhatsGNU: a tool for identifying proteomic novelty
Abstract To understand diversity in enormous collections of genome sequences, we need computationally scalable tools that can quickly contextualize individual genomes based on... -
Expression of ACE2 and a viral virulence-regulating factor CCN family member ...
Abstract It has been reported that coronavirus disease 2019 (COVID-19) causes not only pneumonia but also systemic inflammations including central nervous system (CNS)... -
Prediction of advanced colonic neoplasm in symptomatic patients: a scoring sy...
Abstract Background Fast-track colonoscopy to detect patients with colorectal cancer based on high-risk symptoms is associated with low sensitivity and specificity. The aim was... -
Association of Triglyceride to high-density lipoprotein cholesterol ratio and...
Abstract Background Previous studies have revealed that triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) is one of major risk factors of insulin resistance... -
A genome-wide siRNA screen identifies a druggable host pathway essential for ...
Abstract Background The 2014–2016 Ebola virus (EBOV) outbreak in West Africa highlighted the need for improved therapeutic options against this virus. Approaches targeting host... -
TSS seq based core promoter architecture in blood feeding Tsetse fly (Glossin...
Abstract Background Transcription initiation regulation is mediated by sequence-specific interactions between DNA-binding proteins (transcription factors) and cis-elements,... -
Suppression of endothelial cell migration by tumor associated macrophage-deri...
Abstract Objective To study the mechanism by which epithelial ovarian cancer (EOC)-derived exosomes restore the migration of endothelial cells that is suppressed by TAM-derived... -
Adaptation and psychometric evaluation of the breastfeeding self-efficacy sca...
Abstract Background Increasing the prevalence of optimal breastfeeding practices, including exclusive breastfeeding for 6 months, could prevent an estimated 823,000 child deaths... -
YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodeg...
Abstract Background Ginkgo biloba has been reported to possess free radical-scavenging antioxidant activity and anti-inflammatory properties. In our pilot study, YY-1224, a... -
The extracellular vesicle of gut microbial Paenalcaligenes hominis is a risk ...
Abstract Background In a pilot study, we found that feces transplantation from elderly individuals to mice significantly caused cognitive impairment. Paenalcaligenes hominis and... -
Characterization of novel Bovine Leukemia Virus (BLV) antisense transcripts b...
Abstract Background Bovine Leukemia Virus (BLV) is a deltaretrovirus closely related to the Human T cell leukemia virus-1 (HTLV-1). Cattle are the natural host of BLV where it... -
Mass spectrometry-based identification and whole-genome characterisation of t...
Abstract Background The pteropine orthoreovirus (PRV) was isolated from monkey (Macaca fascicularis) faecal samples collected from human-inhabited areas in Lopburi Province,... -
Relative effects of location relative to the corpus luteum and lactation on t...
Abstract Background Lactation and associated metabolic stresses during the post-partum period have been shown to impair fertility in dairy cows. The oviduct plays key roles in... -
A U-shaped association between the LDL-cholesterol to HDL-cholesterol ratio a...
Abstract Background The low-density lipoprotein cholesterol/high-density lipoprotein- cholesterol (LDL-C/HDL-C) ratio is an excellent predictor of cardiovascular disease (CVD).... -
CD147 increases mucus secretion induced by cigarette smoke in COPD
Abstract Background CD147 is expressed in many tissues and is involved in many inflammatory diseases. Emerging evidence suggests that the overproduction of mucus is a malignant... -
Maternal influences on oral and faecal microbiota maturation in neonatal calv...
Abstract Background The dam is considered an important source of microbes for the calf; consequently, the development of calf microbiota may vary with farming system due to... -
Identification and validation of a Schistosoma japonicum U6 promoter
Abstract Background RNA polymerase III promoters have been widely used to express short hairpin-RNA (shRNA), microRNA (miRNA), and small guide RNA (sgRNA) in gene functional... -
Comparison between two amplicon-based sequencing panels of different scales i...
Abstract Background Sequencing data from The Cancer Genome Atlas (TGCA), the International Cancer Genome Consortium and other research institutes have revealed the presence of... -
Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeuti...
Abstract Background The Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) outbreak originating in Wuhan, China, has raised global health concerns and the...
