38 items found

Types: other Tags: 39999 Chemical Sciences not elsewhere classified Biochemistry Biotechnology Cancer Medicine Physiology Science Policy

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    Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients w...

    Abstract Background Intracellular signaling through cyclic nucleotides, both cyclic AMP and cyclic GMP, is altered in colorectal cancer. Accordingly, it is hypothesized that an...
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    Circulating cathelicidin levels correlate with mucosal disease activity in ul...

    Abstract Background Cathelicidin (LL-37) is an antimicrobial peptide known to be associated with various autoimmune diseases. We attempt to determine if cathelicidin can...
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    Contacting out-of-hours primary care or emergency medical services for time-c...

    Abstract Background Out-of-hours (OOH) healthcare services in Western countries are often differentiated into out-of-hours primary healthcare services (OOH-PC) and emergency...
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    Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and s...

    Abstract Background Cesium-137 (137Cs) is one of the major and most clinically relevant radionuclides of concern in a radiological dispersal device, “dirty bomb” scenario as...
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    Development of a high-throughput screen to identify small molecule enhancers ...

    Abstract Background Duchenne muscular dystrophy (DMD) is caused by loss of sarcolemma connection to the extracellular matrix. Transgenic overexpression of the transmembrane...
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    [18F]tetrafluoroborate as a PET tracer for the sodium/iodide symporter: the i...

    Abstract Background [18F]BF4 −, the first 18F-labelled PET imaging agent for the sodium/iodide symporter (NIS), was produced by isotopic exchange yielding a product with limited...
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    The Ussing chamber system for measuring intestinal permeability in health and...

    Abstract Background The relationship between intestinal epithelial integrity and the development of intestinal disease is of increasing interest. A reduction in mucosal...
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    Autism spectrum disorders, endocrine disrupting compounds, and heavy metals i...

    Abstract Background Evidence has indicated that some non-inherited factors such as exposure to environmental pollutants are associated with neurodevelopment disorders like...
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    Subsequent thyroid disorders associated with treatment strategy in head and n...

    Abstract Background We investigated the risk of thyroid disorders, namely hypothyroidism, thyrotoxicosis and thyroiditis, in head and neck cancer patients undergoing multimodal...
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    Structural Features of Carbons Produced Using Glucose, Lactose, and Saccharose

    Abstract Glucose, lactose, and saccharose were used as precursors to prepare chars at 400 °C then activated at 800 °C or 1000 °C in closed vessels with controlled amounts of...
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    Comparison of calculated remnant lipoprotein cholesterol levels with levels d...

    Abstract Background Remnant cholesterol (RC) can partly explain the residual risk in atherosclerotic cardiovascular disease (ASCVD). A consensus method of measuring RC levels...
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    A systematic review of parent based programs to prevent or reduce alcohol con...

    Abstract Background Adolescent alcohol consumption is an issue of ongoing concern and programs targeting parents have been identified as an important component in minimizing and...
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    The impact of perennial allergic rhinitis with/without allergic asthma on sle...

    Abstract Background Allergic respiratory diseases such as allergic rhinitis (AR) and allergic asthma (AA) are common conditions that can influence sleep and daytime functioning....
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    Role of mesenchymal stem cells, their derived factors, and extracellular vesi...

    Abstract Liver failure is a severe clinical syndrome with a poor prognosis. Mesenchymal stem cell (MSC) transplantation has emerged as a new intervention in treating liver...
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    VEGF-121 plasma level as biomarker for response to anti-angiogenetic therapy ...

    Abstract Background Vascular endothelial growth factor (VEGF) isoforms, particularly the diffusible VEGF-121, could play a major role in the response of recurrent glioblastoma...
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    MicroRNA-181a as novel liquid biopsy marker of central nervous system involve...

    Abstract Background Refractory central nervous system (CNS) involvement is among the major causes of therapy failure in childhood acute leukemia. Applying contemporary...
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    Effects of endogenous sex hormones on lung function and symptom control in ad...

    Abstract Background Although pre-puberty asthma is more prevalent in males, after puberty through middle-age, asthma is more prevalent in females. The surge of sex hormones with...
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    The association of HDL-apoCIII with coronary heart disease and the effect of ...

    Abstract Background Apolipoprotein CIII (apoCIII) is considered to impair the anti-atherogenic effect of high density lipoprotein (HDL) in coronary heart disease (CHD) patients,...
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    Impact of malnutrition on systemic immune and metabolic profiles in type 2 di...

    Abstract Background While obesity and overweight status are firmly established risk factors for Type 2 diabetes mellitus (T2DM), a substantial proportion of diabetic...
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    Evaluation of the association of Wnt signaling with coronary artery calcifica...

    Abstract Background Patients with end-stage renal disease have a higher risk of death from cardiovascular events, which can be mainly attributed to coronary artery calcification...