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Oxidative stress and premature senescence in corneal endothelium following pe...
Abstract Background The purpose of this study was to address the question of how the premature senescence process may affect corneal endothelium after penetrating keratoplasty,... -
Early gut microbiota signature of aGvHD in children given allogeneic hematopo...
Abstract Background The onset of acute Graft-versus-Host Disease (aGvHD) has been correlated with the gut microbiota (GM) composition, but experimental observations are still... -
Dried blood spot versus venous blood sampling for phenylalanine and tyrosine
Abstract Background This study investigated the agreement between various dried blood spot (DBS) and venous blood sample measurements of phenylalanine and tyrosine... -
Exposure to perfluorooctanoic acid (PFOA) decreases neutrophil migration resp...
Abstract Objective Perfluorooctanoic acid (PFOA) is a ubiquitous environmental contaminant and a known immune suppressant in humans and experimental animal models. Studies on... -
The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzhe...
Abstract Background Synaptic degeneration is a central pathogenic event in Alzheimer’s disease that occurs early during the course of disease and correlates with cognitive... -
Genome-wide DNA methylation at birth in relation to in utero arsenic exposure...
Abstract Background In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life.... -
Patternable particle microarray utilizing controllable particle delivery
Abstract In this study, we demonstrate an on-demand delivering and sequential arraying of single microparticles utilizing multiple pneumatic pressure-driven elastomer valves and... -
Comparison of faecal microbiota in Blastocystis-positive and Blastocystis-neg...
Abstract Background We investigated whether the carriage of Blastocystis in IBS patients was associated with differences in the faecal microbiota. Forty patients with... -
External quality assessment (EQA) program for the immunohistochemical detecti...
Abstract Background An External Quality Assessment (EQA) program was developed to investigate the status of estrogen receptor (ER), progesterone receptor (PR), and Ki-67... -
Assessment of blood levels of heavy metals including lead and manganese in he...
Abstract Background Exposure to environmental heavy metals is common among African children. Although many of these metals are known neurotoxicants, to date, monitoring of this... -
Comparison of biochemical parameters among DPP4 inhibitor users and other ora...
Abstract Background Higher efficacy of incretin-based therapies for type 2 diabetes mellitus has been reported from Asia. Pancreatitis and hepatitis have also been suspected to... -
Combining adverse pregnancy and perinatal outcomes for women exposed to antie...
Abstract Background Application of latent variable models in medical research are becoming increasingly popular. A latent trait model is developed to combine rare birth defect... -
Reduced DNA methylation of the oxytocin receptor gene is associated with obse...
Abstract Background Oxytocin is an important neuromodulator involved in cognition and socio-emotional processing that exerts its central activities via oxytocin receptors.... -
Synthesis of graphene oxide-quaternary ammonium nanocomposite with synergisti...
Abstract Background Bacterial infection is one of the most common complications in burn, trauma, and chronic refractory wounds and is an impediment to healing. The frequent... -
Adaptive optics optical coherence tomography angiography for morphometric ana...
Histological studies have shown that morphometric changes at the microscopic level of choriocapillaris (CC) occur with aging and disease onset, and therefore may be sensitive... -
Factors analysis on the use of key quality indicators for narrowing the gap o...
Abstract Background There are differences in the quality of care among breast cancer patients. Narrowing the quality differences could be achieved by increasing the utilization... -
A study of the different parameters in acute and chronic Budd–Chiari syndrome
Abstract Background Budd–Chiari syndrome (BCS) is a rare and potentially life-threatening vascular disease of the liver. There are a few studies on the differences between acute... -
Plasma matrix metalloproteinases are associated with incident cardiovascular ...
Abstract Background Altered regulation of extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) may contribute to... -
Prenatal alcohol exposure and infant gross motor development: a prospective c...
Abstract Background Maternal alcohol consumption in pregnancy may have adverse effects on child gross motor (GM) development. There have been few human studies on this topic,... -
Obstetric triage systems: a systematic review of measurement properties (Clin...
Abstract Background Since labor and delivery units often serve as emergency units for pregnant women, the use of obstetric triage systems with poor or inadequate quality can...