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Patternable particle microarray utilizing controllable particle delivery
Abstract In this study, we demonstrate an on-demand delivering and sequential arraying of single microparticles utilizing multiple pneumatic pressure-driven elastomer valves and... -
Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate...
Abstract Background Dexketoprofen trometamol plus tramadol hydrochloride is a new oral combination of two analgesics, which have different mechanisms of action for the treatment... -
Identification of G-quadruplex structures that possess transcriptional regula...
Abstract Background G-quadruplex is a DNA secondary structure that has been shown to play an important role in biological systems. In a previous study, we identified 1998... -
Gene expression of the liver of vaccination-protected mice in response to ear...
Abstract Background The role of the liver for survival of blood-stage malaria is only poorly understood. In experimental blood-stage malaria with Plasmodium chabaudi, protective... -
Prevalence of G6PD deficiency and Plasmodium falciparum parasites in asymptom...
Abstract Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked genetic disorder that results in impaired enzyme activity. Although G6PD deficiency is... -
Quantification of microRNA in plasma using probe based TaqMan assays: is micr...
Abstract Objective Circulating microRNAs are promising diagnostics and prognostics biomarkers in a wide variety of diseases. However, there is a critical reproducibility... -
New insights on serodiagnosis of trichinellosis during window period: early d...
Abstract The clinical diagnosis of trichinellosis is difficult because its clinical manifestations are nonspecific. Detection of anti-Trichinella IgG by ELISA using T. spiralis... -
Virulence factor RNA transcript expression in the Leishmania Viannia subgenus...
Abstract Background Leishmania RNA virus-1 (LRV1) is a double-stranded RNA virus identified in 20–25% of Viannia—species endemic to Latin America, and is believed to accelerate... -
Role of mesenchymal stem cells, their derived factors, and extracellular vesi...
Abstract Liver failure is a severe clinical syndrome with a poor prognosis. Mesenchymal stem cell (MSC) transplantation has emerged as a new intervention in treating liver... -
The Trypanosomatid Pr77-hallmark contains a downstream core promoter element ...
Abstract Background Trypanosomatid genomes are highly colonized by non-LTR retroelements that make up to 5 % of the nuclear genome. These elements are mainly accumulated in the... -
Effects of Peutz-Jeghers syndrome (PJS) causing missense mutations L67P, L182...
The Liver kinase B1 (LKB1) is encoded by LKB1 gene. Several pathogenic mutations of LKB1 causing Peutz-Jeghers syndrome (PJS) and also cancers in breast, gastric, pancreas and... -
SLC11A1 polymorphisms and host susceptibility to cutaneous leishmaniasis in P...
Abstract Background The vector-borne cutaneous leishmaniasis (CL) is endemic in several regions of Pakistan mainly affecting poor populations. Host genetic factors, particularly... -
Evaluation of rapid extraction and isothermal amplification techniques for th...
Abstract Background Leishmaniasis is a disease caused by vector-borne protozoans. In Sri Lanka, the cutaneous form of the disease is predominant, which is usually diagnosed... -
Identification of replication-dependent and replication-independent linker hi...
Abstract Background There are 11 variants of linker histone H1 in mammalian cells. Beyond their shared abilities to stabilize and condense chromatin, the H1 variants have been... -
Evaluation of folate receptor 1 (FOLR1) mRNA expression, its specific promote...
Abstract Background In this retrospective study we evaluated the respective correlations and clinical relevance of FOLR1 mRNA expression, FOLR1 promoter specific methylation and... -
Invasive DNA elements modify the nuclear architecture of their insertion site...
Abstract Background The three-dimensional (3D) organization of chromosomes is linked to epigenetic regulation and transcriptional activity. However, only few functional features...
