-
Helios + Regulatory T cell frequencies are correlated with control of viral r...
Abstract Background The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation.... -
Increased calcium intake is associated lower serum 25-hydroxyvitamin D levels...
Abstract Background There are indications that an increased intake of calcium has a vitamin D sparing effect, which might be explained by a decreased catabolism of... -
Estimating the cost-effectiveness of daclatasvir + sofosbuvir versus sofosbuv...
Abstract Background As treatments for chronic hepatitis C are moving away from interferon-containing regimens, the most appropriate allocation of resources to higher cost,... -
Comparison of weighting approaches for genetic risk scores in gene-environmen...
Abstract Background Weighted genetic risk scores (GRS), defined as weighted sums of risk alleles of single nucleotide polymorphisms (SNPs), are statistically powerful for... -
Assessment of research waste part 1: an exemplar from examining study design,...
Abstract Background Research waste is estimated to be very common, but assessments of its prevalence and scope are rare. As an example, we assessed research waste in clinical... -
Healthcare utilization and direct costs of non-infectious comorbidities in HI...
Objective: To estimate the incremental healthcare utilization and costs associated with common non-infectious comorbid conditions among commercially and Medicaid-insured... -
Long-term overall survival and prognostic score predicting survival: the IMPA...
Abstract Background In 2007, we initiated IMPACT, a precision medicine program for patients referred for participation in early-phase clinical trials. We assessed the... -
Respiratory virus-associated infections in HIV-infected adults admitted to th...
Abstract Introduction Acute respiratory failure is the main reason for admission to the intensive care unit (ICU) in HIV-infected adults. There is little data about the... -
Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin-based combin...
Abstract Background Activation of hypnozoites of vivax malaria causes multiple clinical relapses, which contribute to the Plasmodium vivax burden and continuing transmission.... -
Gender disparity in epidemiological trend of HIV/AIDS infection and treatment...
Abstract Background The HIV/AIDS epidemic has been fuelled by gender inequality and disparity resulted in violation of women reproductive right. The â feminizationâ of the... -
Development of a recombinase polymerase amplification combined with a lateral...
Abstract Background Mycoplasma bovis (M. bovis) is a major etiological agent of bovine mycoplasmosis around the world. Point-of-care testing in the field is lacking owing to the... -
Effect of delayed misoprostol dosing interval for induction of labor: a retro...
Abstract Background Induction of labor occurs in greater than 22% of all pregnancies in the United States. Previous studies have shown that misoprostol is more effective for... -
Helicobacter pylori infection as a risk factor for serum bilirubin change and...
Abstract Background Helicobacter pylori infection is associated with several extragastric conditions including dyslipidemia and metabolic syndrome. This study aimed to... -
Chlorhexidine bathing and health care-associated infections among adult inten...
Abstract Background Health care-associated infections (HAI) have been shown to increase length of stay, the cost of care, and rates of hospital deaths (Kaye and Marchaim, J Am... -
Involvement of DPP9 in gene fusions in serous ovarian carcinoma
Abstract Background A fusion gene is a hybrid gene consisting of parts from two previously independent genes. Chromosomal rearrangements leading to gene breakage are frequent in... -
Sheep breed and shearing influences attraction and blood-feeding behaviour of...
Abstract Background Culicoides biting midges (Diptera: Ceratopogonidae) are responsible for the biological transmission of arboviruses of international importance between... -
Role of ethambutol and rifampicin in the treatment of Mycobacterium avium com...
Abstract Background A three-drug regimen (macrolide, ethambutol, and rifampicin) is recommended for the treatment of Mycobacterium avium complex pulmonary disease (MAC-PD).... -
Varicella zoster virus-associated morbidity and mortality in Africa â a sys...
Abstract Background Varicella zoster virus (VZV) causes varicella and herpes zoster. These vaccine preventable diseases are common globally. Most available data on VZV... -
Vaginal, sexual and urinary symptoms following hysterectomy: a multi-centre r...
Abstract Background Hysterectomy is the most common major gynaecological procedure. The aim of this study was to study vaginal, sexual and urinary symptoms following total... -
Very low sensitivity of wet mount microscopy compared to PCR against culture ...
Abstract Background Trichomonas vaginalis (TV) causes the Trichomoniasis Syndrome composed of vaginitis in women, urethritis in men and tube infection in both sexes. This...
