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Improving engagement with healthcare in hepatitis C: a randomised controlled ...
Abstract Background Peer support can enable patient engagement with healthcare services, particularly for marginalised populations. In this randomised controlled trial, the... -
Depression comorbid with tuberculosis and its impact on health status: cross-...
Abstract Background Depression in tuberculosis increases the risk for adverse health outcomes. However, little is known about comorbid depression and tuberculosis in the general... -
Assessment of eating disorders with the diabetes eating problems survey – rev...
Abstract Background The purpose of the study was to evaluate in a sample of insulin-treated diabetic patients, with type 1 or type 2 diabetes, the psychometric characteristics... -
Cherenkov luminescence imaging is a fast and relevant preclinical tool to ass...
Abstract Purpose Molecular imaging techniques visualise biomarkers for both drug development and personalised medicine. In this field, Cherenkov luminescence imaging (CLI) seems... -
Scl-Ab reverts pro-osteoclastogenic signalling and resorption in estrogen def...
Abstract Background Neutralising antibodies to sclerostin (Scl-Ab) have shown significant potential to induce bone formation and decrease bone resorption, increase strength and... -
Appendectomy, cholecystectomy and diagnostic laparoscopy conducted before pre...
Abstract Background Non-obstetric surgery conducted during pregnancy may increase the risk of adverse birth outcomes like small for gestational age, preterm birth, and... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Saliva exosomes-derived UBE2O mRNA promotes angiogenesis in cutaneous wounds ...
Abstract Background Enhancing angiogenesis is critical for accelerating wound healing. Application of different types of exosomes (Exos) to promote angiogenesis represents a... -
Reduced DNA methylation of the oxytocin receptor gene is associated with obse...
Abstract Background Oxytocin is an important neuromodulator involved in cognition and socio-emotional processing that exerts its central activities via oxytocin receptors.... -
Buying and selling human eggs: infertility providers’ ethical and other conce...
Abstract Background Egg donor agencies are increasingly being used as part of IVF in the US, but are essentially unregulated, posing critical ethical and policy questions... -
Transcriptionally promiscuous "blurry" promoters in Tc1/mariner transposons a...
Abstract Background We have recently described a peculiar feature of the promoters in two Drosophila Tc1-like elements, Bari1 and Bari3. The AT-richness and the presence of weak... -
Peripheral cathepsin L inhibition induces fat loss in C. elegans and mice thr...
Abstract Background Cathepsin L and some other cathepsins have been implicated in the development of obesity in humans and mice. The functional inactivation of the proteases... -
Relationship between age and bronchodilator response at diagnosis in adult-on...
Abstract Background Possible variation in bronchodilator response (BDR) according to age at the diagnosis of adult-onset asthma is unknown. Our aim was to assess if BDR in FEV1... -
The NuA4 acetyltransferase and histone H4 acetylation promote replication rec...
Abstract Background Histone acetylation plays an important role in DNA replication and repair because replicating chromatin is subject to dynamic changes in its structures.... -
Suppression of LPS-induced tau hyperphosphorylation by serum amyloid A
Abstract Background Accumulation of hyperphosphorylated tau is a major neuropathological feature of tauopathies including Alzheimer’s disease (AD). Serum amyloid A (SAA), an... -
Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in p...
Abstract Background Transient receptor potential ankyrin 1 (TRPA1) is a membrane-associated cation channel, widely expressed in neuronal cells and involved in nociception and... -
EWS and FUS bind a subset of transcribed genes encoding proteins enriched in ...
Abstract Background FUS (TLS) and EWS (EWSR1) belong to the FET-protein family of RNA and DNA binding proteins. FUS and EWS are structurally and functionally related and... -
Meaning in life: resilience beyond reserve
Abstract Background The contribution of psychological factors to brain health and resilience remains poorly investigated. Furthermore, their possible interaction with â... -
Standards not that standard
Abstract There is a general assent on the key role of standards in Synthetic Biology. In two consecutive letters to this journal, suggestions on the assembly methods for the... -
Memory retrieval in addiction: a role for miR-105-mediated regulation of D1 r...
Abstract Background Drug addiction is a chronic brain disorder characterized by the compulsive use of drugs. The study of chronic morphine-induced adaptation in the brain and...
