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Identifying targets for antibiotic stewardship interventions through analysis...
Abstract Background In order to change antibiotic prescribing behaviour, we need to understand the prescribing process. The aim of this study was to identify targets for... -
Use of diagnostic tests and the appropriateness of the treatment decision in ...
Abstract Background Inappropriate prescription of antibiotics is the leading driver of antimicrobial resistance (AMR). The majority of antibiotics are prescribed in primary... -
Cortical vein thrombosis in adult patients of cerebral venous sinus thrombosi...
Abstract Background Cortical vein thrombosis (CVT) receives little attention in adult patients with cerebral venous sinus thrombosis (CVST). This study aimed to investigate the... -
Transcriptionally induced enhancers in the macrophage immune response to Myco...
Abstract Background Tuberculosis is a life-threatening infectious disease caused by Mycobacterium tuberculosis (M.tb). M.tb subverts host immune responses to build a favourable... -
Activation of innate immune genes in caprine blood leukocytes after systemic ...
Abstract Background Sepsis is a serious health problem associated with a range of infectious diseases in animals and humans. Early events of this syndrome can be mimicked by... -
Epidemiology of burns in pediatric patients of Beijing City
Abstract Background This study aimed to assess the epidemiological characteristics of pediatric burns in Beijing City. Methods This was a retrospective study of pediatric... -
A prebiotic intervention study in children with autism spectrum disorders (ASDs)
Abstract Background Different dietary approaches, such as gluten and casein free diets, or the use of probiotics and prebiotics have been suggested in autistic spectrum... -
Combination of Ranibizumab with macular laser for macular edema secondary to ...
Abstract Background It is not clear whether macular laser combined with anti-vascular endothelial growth factor (VEGF) can reduce the number of anti-VEGF injections in the... -
Prone positioning in severe ARDS requiring extracorporeal membrane oxygenation
Abstract Background Prone positioning (PP) has shown to improve survival in patients with severe acute respiratory distress syndrome (ARDS). To this point, it is unclear if PP... -
The role of human Metapneumovirus genetic diversity and nasopharyngeal viral ...
Abstract Background Human metapneumovirus (HMPV) is established as one of the causative agents of respiratory tract infections. To date, there are limited reports that describe... -
Pervasive read-through transcription of T-DNAs is frequent in tobacco BY-2 ce...
Abstract Background Plant transformation via Agrobacterium tumefaciens is characterized by integration of commonly low number of T-DNAs at random positions in the genome. When... -
The role of antifungals in the management of patients with severe asthma
Abstract In patients with asthma, the inhalation of elevated amounts of fungal spores and hyphae may precipitate the onset of asthma or worsen control to the extent of being... -
Cumulative fluid accumulation is associated with the development of acute kid...
Abstract Background Acute kidney injury (AKI) is common in patients in the intensive care unit (ICU) and may be present on admission or develop during ICU stay. Our objectives... -
Oxidative stress enhances the expression of IL-33 in human airway epithelial ...
Abstract Background Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, and its possible involvement in the pathophysiology of COPD and viral-induced... -
Divergent transcriptomic responses underlying the ranaviruses-amphibian inter...
Abstract Background Ranaviruses (family Iridoviridae, nucleocytoplasmic large DNA viruses) have been reported as promiscuous pathogens of cold-blooded vertebrates. Rana grylio... -
Ubiquitous giants: a plethora of giant viruses found in Brazil and Antarctica
Abstract Background Since the discovery of giant viruses infecting amoebae in 2003, many dogmas of virology have been revised and the search for these viruses has been... -
Respiratory virus-associated infections in HIV-infected adults admitted to th...
Abstract Introduction Acute respiratory failure is the main reason for admission to the intensive care unit (ICU) in HIV-infected adults. There is little data about the... -
Antibiotics prescription and guidelines adherence in elderly: impact of the c...
Abstract Background Although the interest of antibiotics is well known, antibiotics prescription is associated with side effect, especially in patients with multiples... -
A transgenerational role of the germline nuclear RNAi pathway in repressing h...
Abstract Background Environmental stress-induced transgenerational epigenetic effects have been observed in various model organisms and human. The capacity and mechanism of such... -
Comparison among ACR1997, SLICC and the new EULAR/ACR classification criteria...
Abstract Background To date there are no specific classification criteria for childhood-onset systemic lupus erythematosus (cSLE). This study aims to compare the performance...
