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Scl-Ab reverts pro-osteoclastogenic signalling and resorption in estrogen def...
Abstract Background Neutralising antibodies to sclerostin (Scl-Ab) have shown significant potential to induce bone formation and decrease bone resorption, increase strength and... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Incidence and diagnosis of Acute kidney injury in hospitalized adult patients...
Abstract Background Acute kidney injury (AKI) places a heavy burden on the healthcare system in China and is usually misdiagnosed. However, there are limited studies that have... -
Transcriptionally promiscuous "blurry" promoters in Tc1/mariner transposons a...
Abstract Background We have recently described a peculiar feature of the promoters in two Drosophila Tc1-like elements, Bari1 and Bari3. The AT-richness and the presence of weak... -
Involving general practice trainees in clinical practice guideline adaptation
Abstract Background It is unclear whether it is feasible to involve residents in guideline development or adaptation. We designed a multifaceted training program that combines... -
Cumulative fluid accumulation is associated with the development of acute kid...
Abstract Background Acute kidney injury (AKI) is common in patients in the intensive care unit (ICU) and may be present on admission or develop during ICU stay. Our objectives... -
Configurations for obtaining in-consultation assistance from supervisors in g...
Abstract Background General practice (GP) trainees may seek supervisor assistance to complete their patient consultations. This in-consultation assistance plays a key role in... -
INSPECT: extending plane-casting for 6-DOF control
Abstract INSPECT is a novel interaction technique for 3D object manipulation using a rotation-only tracked touch panel. Motivated by the applicability of the technique on... -
TSS seq based core promoter architecture in blood feeding Tsetse fly (Glossin...
Abstract Background Transcription initiation regulation is mediated by sequence-specific interactions between DNA-binding proteins (transcription factors) and cis-elements,... -
An analysis of national collaboration with Spanish researchers abroad in the ...
Abstract Background The establishment of scientific collaborations with researchers abroad can be considered a good practice to make appropriate use of their knowledge and to... -
Challenges with study procedure fidelity when conducting household survey: re...
Abstract Objectives The aim of the study was to identify reasons for protocol deviations during conduct of large epidemiological surveys despite training of field workers,... -
Cardiovascular secondary prevention in high-risk patients: a randomized contr...
Abstract Background Enhanced cardiovascular secondary preventive follow-up is needed to improve adherence to recommended low-density lipoprotein cholesterol (LDL-C) and blood... -
Molecular mechanism of the priming by jasmonic acid of specific dehydration s...
Abstract Background Plant genes that provide a different response to a similar dehydration stress illustrate the concept of transcriptional ‘dehydration stress memory’.... -
Automation bias in electronic prescribing
Abstract Background Clinical decision support (CDS) in e-prescribing can improve safety by alerting potential errors, but introduces new sources of risk. Automation bias (AB)... -
Comparative effectiveness of immunosuppressive drugs and corticosteroids for ...
Abstract Background There is a lack of high-quality meta-analyses and network meta-analyses of immunosuppressive drugs for lupus nephritis. Our objective was to assess the... -
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent periphera...
Abstract Background Chronic alcohol consumption is associated with neuroinflammation, neuronal damage, and behavioral alterations including addiction. Alcohol-induced... -
Racial and ethnic differences in smoking changes after chronic disease diagno...
Abstract Background Middle-aged and older Americans from underrepresented racial and ethnic backgrounds are at risk for greater chronic disease morbidity than their white... -
Factors associated with prolonged length of stay for elective hepatobiliary a...
Abstract Background Patients with prolonged length of hospital stay (LOS) not only increase their risks of nosocomial infections but also deny other patients access to inpatient... -
Informing urban climate planning with high resolution data: the Hestia fossil...
Abstract Background Cities contribute more than 70% of global anthropogenic carbon dioxide (CO2) emissions and are leading the effort to reduce greenhouse gas (GHG) emissions... -
Parental smoking and blood pressure in children and adolescents: a national c...
Abstract Background Current evidence on the health effects of passive smoking on childhood blood pressure is limited and inconsistent. We investigated the associations between...
