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Prevalence and characteristics of older adults with a persistent death wish w...
Abstract Background Some older persons develop a persistent death wish without being severely ill, often referred to as “completed life” or “tiredness of life”. In the... -
Erythropoietin as an add-on treatment for cognitive side effects of electroco...
Abstract Background Electroconvulsive therapy (ECT) is the most effective treatment for severe depression, but its use is impeded by its cognitive side effects. Novel treatments... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Degree of dyspnoea at admission and discharge in patients with heart failure ...
Abstract Background Dyspnoea is a disabling symptom in patients admitted with heart failure (HF) and respiratory diseases (RD). The main aim of this study is to evaluate its... -
Systematic review of outcome domains and instruments used in clinical trials ...
Abstract Background There is no evidence-based guidance to facilitate design decisions for confirmatory trials or systematic reviews investigating treatment efficacy for adults... -
Effect of smoking status on lung function, patient-reported outcomes, and saf...
Abstract Background Smoking is a major risk factor for COPD and may impact the efficacy of COPD treatments; however, a large proportion of COPD patients continue to smoke... -
Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in p...
Abstract Background Transient receptor potential ankyrin 1 (TRPA1) is a membrane-associated cation channel, widely expressed in neuronal cells and involved in nociception and... -
Postpartum women’s use of medicines and breastfeeding practices: a systematic...
Abstract The objectives of this article are to systematically review i) the extent of medicine use in postpartum women, and ii) the impact of maternal medicine use (excluding... -
Do Cochrane summaries help student midwives understand the findings of Cochra...
Abstract Background Abstracts and plain language summaries (PLS) are often the first, and sometimes the only, point of contact between readers and systematic reviews. It is... -
The smoking cessation in pregnancy incentives trial (CPIT): study protocol fo...
Abstract Background Eighty per cent of UK women have at least one baby, making pregnancy an opportunity to help women stop smoking before their health is irreparably... -
Clinical guidelines for the management of treatment-resistant depression: Fre...
Abstract Background Clear guidance for successive antidepressant pharmacological treatments for non-responders in major depression is not well established. Method Based on the... -
Efficacy of acupuncture in the prevention and treatment of chemotherapy-induc...
Abstract Background Chemotherapy-induced nausea and vomiting (CINV) is a common and distressing side effect. We conducted this clinical trial to compare the effectiveness of... -
Prescription drug use and potential teratogenicity risk among pregnant women ...
Abstract Objective To investigate medications prescribed for pregnant women and their potential teratogenicity risk in Kemisse General Hospital. Result A total of 263 medical... -
A toolset of constitutive promoters for metabolic engineering of Rhodosporidi...
Abstract Background Rhodosporidium toruloides is a promising host for the production of bioproducts from lignocellulosic biomass. A key prerequisite for efficient pathway... -
Cosmetic outcome as rated by patients, doctors, nurses and BCCT.core software...
Abstract Background The purpose of this research was to assess agreement between four rating systems of cosmetic outcome measured in a subset of patients with early breast... -
A Combined Randomised and Observational Study of Surgery for Fractures In the...
Abstract Background We are performing a combined randomised and observational study comparing internal fixation to non-surgical management for common wrist fractures in older... -
Comparative effectiveness of levetiracetam, valproate and carbamazepine among...
Abstract Background Few clinical trials have evaluated the efficacy and tolerability of antiepileptic drugs (AEDs) as initial monotherapy for elderly patients. Methods This... -
Correlates of alcoholics anonymous affiliation among justice-involved women
Abstract Background Alcohol use disorder (AUD) constitutes a major public health problem and is associated with a substantial amount of disability and premature death worldwide.... -
Internists‘ career choice towards primary care: a cross-sectional survey
Abstract Background Swiss primary care (PC) is facing workforce shortage. Up to 2011 this workforce was supplied by two board certifications: general medicine and internal... -
Complementary and alternative medicine use amongst patients with cardiovascul...
Abstract Background Data on complementary and alternative medicine (CAM) use in patients with cardiovascular disease (CVD) are lacking. We aim to investigate the prevalence of...
