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Structural alteration of DNA induced by viral protein R of HIV-1 triggers the...
Abstract Background Viral protein R (Vpr) is an accessory protein of HIV-1, which is potentially involved in the infection of macrophages and the induction of the... -
Influenza A virus enhances ciliary activity and mucociliary clearance via TLR...
Abstract Background Viral respiratory tract infections, such as influenza A virus (IAV), are common and life-threatening illnesses worldwide. The mechanisms by which viruses are... -
Isolation and functional validation of the CmLOX08 promoter associated with s...
Abstract Background Lipoxygenases (LOXs) play significant roles in abiotic stress responses, and identification of LOX gene promoter function can make an important contribution... -
High-throughput sequencing of small RNAs revealed the diversified cold-respon...
Abstract Background Cold stress is one of the most severe abiotic stresses affecting the banana production. Although some miRNAs have been identified, little is known about the... -
Microbial community shifts elicit inflammation in the caecal mucosa via the G...
Abstract Background Dietary structure in ruminants is closely connected with the composition of gastrointestinal microbiota. Merging study has shown that dietary induced SARA... -
Examining the role of spatial skills and mathematics motivation on middle sch...
Abstract Background Spatial skills and mathematical ability have been repeatedly identified as critical for achievement in Science, Technology, Engineering, and Mathematics... -
The HDAC6/APOBEC3G complex regulates HIV-1 infectiveness by inducing Vif auto...
Abstract Background Human immunodeficiency virus type 1 (HIV-1) has evolved a complex strategy to overcome the immune barriers it encounters throughout an organism thanks to its... -
Evaluation of apoptosis imaging biomarkers in a genetic model of cell death
Abstract Purpose We have previously developed the caspase-based radiotracer, 18F-ICMT-11, for PET imaging to monitor treatment response. We further validated 18F-ICMT-11... -
Inhibition of RNA polymerase II allows controlled mobilisation of retrotransp...
Abstract Background Retrotransposons play a central role in plant evolution and could be a powerful endogenous source of genetic and epigenetic variability for crop breeding. To... -
CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer
Abstract Background DNA repair of alkylation damage is defective in various cancers. This occurs through somatically acquired inactivation of the MGMT gene in various cancer... -
DDX5 potentiates HIV-1 transcription as a co-factor of Tat
Abstract Background HIV-1 does not encode a helicase and hijacks those of the cell for efficient replication. We and others previously showed that the DEAD box helicase, DDX5,... -
DARLING: a device for assessing resistance to lodging in grain crops
Abstract Background Stalk lodging (breakage of plant stems prior to harvest) is a major problem for both farmers and plant breeders. A limiting factor in addressing this problem... -
A novel FLI1 exonic circular RNA promotes metastasis in breast cancer by coor...
Abstract Background Friend leukemia virus integration 1 (FLI1), an ETS transcription factor family member, acts as an oncogenic driver in hematological malignancies and promotes...
