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The NuA4 acetyltransferase and histone H4 acetylation promote replication rec...
Abstract Background Histone acetylation plays an important role in DNA replication and repair because replicating chromatin is subject to dynamic changes in its structures.... -
How much allopurinol does it take to get to target urate? Comparison of actua...
Abstract Objective Allopurinol dosing has frequently been limited based on creatinine clearance (CrCL), resulting in failure to achieve target serum urate (SU). The aim of this... -
Associations within school-based same-sex friendship networks of children’s p...
Abstract Background Physical activity in children is associated with better physical and mental health but many children do not meet physical activity guidelines. Friendship... -
Building damage survey and microtremor measurements for the source region of ...
Abstract We performed a damage survey of buildings and carried out microtremor observations in the source region of the 2015 Gorkha earthquake. Our survey area spans the... -
Fluid status evaluation by inferior vena cava diameter and bioimpedance spect...
Abstract Background Evaluation of patient’s dry weight remains challenging in chronic hemodialysis (HD) especially in children. Inferior Vena Cava (IVC) measurement was reported... -
A cluster randomized controlled trial comparing the effectiveness of an indiv...
Abstract Background Most adolescents do not meet the recommendations for physical activity (PA) of at least 1 h per day. Individual planning (IP) interventions, including... -
Lysosome trafficking is necessary for EGF-driven invasion and is regulated by...
Abstract Background Tumor invasion through a basement membrane is one of the earliest steps in metastasis, and growth factors, such as Epidermal Growth Factor (EGF) and... -
Targeting tauopathy with engineered tau-degrading intrabodies
Abstract Background The accumulation of pathological tau is the main component of neurofibrillary tangles and other tau aggregates in several neurodegenerative diseases,... -
Duox mediates ultraviolet injury-induced nociceptive sensitization in Drosoph...
Abstract Background Nociceptive sensitization is an increase in pain perception in response to stimulus. Following brief irradiation of Drosophila larvae with UV, nociceptive... -
Perfusion fixation in brain banking: a systematic review
Abstract Background Perfusing fixatives through the cerebrovascular system is the gold standard approach in animals to prepare brain tissue for spatial biomolecular profiling,... -
DARLING: a device for assessing resistance to lodging in grain crops
Abstract Background Stalk lodging (breakage of plant stems prior to harvest) is a major problem for both farmers and plant breeders. A limiting factor in addressing this problem...
