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Oxidative stress and premature senescence in corneal endothelium following pe...
Abstract Background The purpose of this study was to address the question of how the premature senescence process may affect corneal endothelium after penetrating keratoplasty,... -
Compliance with water advisories after water outages in Norway
Background: Water advisories, especially those concerning boiling drinking water, are widely used to reduce risks of infection from contaminants in the water supply. Since the... -
Patient’s perception of kidney stone prevention within the emergency departme...
Abstract Background No known data in the literature assessing practice of kidney stone prevention in the emergency department (ED) is available. Objectives Assess patient... -
Association between antibiotic consumption and the rate of carbapenem-resista...
Abstract Background This study aimed to investigate the relationship between the rate of carbapenem-resistant Gram-negative bacteria and antibiotic consumption intensity in 153... -
Exploring why global health needs are unmet by research efforts: the potentia...
Abstract Background It has been well established that research is not addressing health needs in a balanced way — much more research is conducted on diseases with more burden in... -
The effect of regularly dosed paracetamol versus no paracetamol on renal func...
Abstract Background Plasmodium knowlesi is the most common cause of human malaria in Malaysia. Acute kidney injury (AKI) is a frequent complication. AKI of any cause can have... -
Comparison of efficacy and safety of drug-eluting versus uncoated balloon ang...
Abstract Background This quantitative meta-analysis was conducted to evaluate the efficacy and safety of drug-eluting balloon (DEB) vs. uncoated balloon (UCB) in patients with... -
Dimethyl fumarate attenuates reactive microglia and long-term memory deficits...
Abstract Background Systemic inflammation is associated with increased cognitive decline and risk for Alzheimer’s disease. Microglia (MG) activated during systemic inflammation... -
Risk factors influencing survival of acellular porcine corneal stroma in infe...
Abstract Background A worldwide lack of donor corneas demands the bioengineered corneas be developed as an alternative. The primary objective of the current study was to... -
Plasma matrix metalloproteinases are associated with incident cardiovascular ...
Abstract Background Altered regulation of extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) may contribute to... -
Selection of reliable reference genes for the normalisation of gene expressio...
Abstract Background Macrophages are key players in the initiation, perpetuation and regulation of both innate and adaptive immune responses. They largely perform these roles... -
The face of Ebola: changing frequency of haemorrhage in the West African comp...
Abstract Background The West-African (WA) Zaire Ebolavirus disease (EVD) outbreak was characterized by an exceptionally high number of cases and deaths as compared with the... -
Involving general practice trainees in clinical practice guideline adaptation
Abstract Background It is unclear whether it is feasible to involve residents in guideline development or adaptation. We designed a multifaceted training program that combines... -
Diabetic retinopathy is associated with the presence and burden of subclinica...
Abstract Background Cardiovascular (CV) disease due to atherosclerosis is a major cause of morbidity and mortality in adult patients with diabetes, either type 1 or type 2... -
Preparing the next generation of genomicists: a laboratory-style course in me...
Abstract The growing gap between the demand for genome sequencing and the supply of trained genomics professionals is creating an acute need to develop more effective genomics... -
Quantitative analysis of a rare disease network’s international contact datab...
Abstract Background Castleman disease (CD) describes a group of rare and poorly understood lymphoproliferative disorders that include unicentric CD (UCD), Human Herpes Virus-8... -
Clinical characteristics of the patients with bacteremia due to Moraxella cat...
Abstract Background Invasive diseases due to Moraxella catarrhalis are rare in children, even in immunocompromised hosts. Therefore, data regarding clinical characteristics and... -
Differential roles for pathogenicity islands SPI-13 and SPI-8 in the interact...
Abstract Background Salmonella pathogenicity island (SPI)-13 is conserved in many serovars of S. enterica, including S. Enteritidis, S. Typhimurium and S. Gallinarum. However,... -
A cross-sectional study assessing the association between online ratings and ...
Abstract Background Even though physician rating websites (PRWs) have been gaining in importance in both practice and research, little evidence is available on the association... -
Distinct core promoter codes drive transcription initiation at key developmen...
Abstract Background Development is largely driven by transitions between transcriptional programs. The initiation of transcription at appropriate sites in the genome is a key...
