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Time to appropriate antibiotic therapy is a predictor of outcome in patients ...
Abstract Background Bloodstream infections (BSIs) by Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae (Kp) are associated with high mortality. The aim... -
Classifying publications from the clinical and translational science award pr...
Abstract Background Translational research is a key area of focus of the National Institutes of Health (NIH), as demonstrated by the substantial investment in the Clinical and... -
Patternable particle microarray utilizing controllable particle delivery
Abstract In this study, we demonstrate an on-demand delivering and sequential arraying of single microparticles utilizing multiple pneumatic pressure-driven elastomer valves and... -
Retrospective analysis in oculocutaneous albinism patients for the 2.7 kb del...
Abstract Background Oculocutaneous albinism (OCA) is an autosomal recessive disorder. A significant portion of OCA patients has been found with a single pathogenic variant... -
The magnitude of antibiotic resistance to Helicobacter pylori in Africa and i...
Abstract Background Worldwide Helicobacter pylori (H.pylori) treatment is of great challenge due to increased antibiotic resistance. The burden of H. pylori antibiotic... -
Saliva exosomes-derived UBE2O mRNA promotes angiogenesis in cutaneous wounds ...
Abstract Background Enhancing angiogenesis is critical for accelerating wound healing. Application of different types of exosomes (Exos) to promote angiogenesis represents a... -
Prevalence and antibiotic resistance of bacteria isolated from the cerebrospi...
Abstract Background Postoperative central nervous system infections (PCNSIs) represent a serious complication, and the timely use of antibiotics guided by the identification of... -
Synthesis of graphene oxide-quaternary ammonium nanocomposite with synergisti...
Abstract Background Bacterial infection is one of the most common complications in burn, trauma, and chronic refractory wounds and is an impediment to healing. The frequent... -
Systematic review of time trends in the prevalence of Helicobacter pylori inf...
Abstract It has been suggested that the prevalence of Helicobacter pylori infection has stabilized in the USA and is decreasing in China. We conducted a systematic literature... -
Acanthamoeba containing endosymbiotic chlamydia isolated from hospital enviro...
Abstract Background Environmental chlamydiae belonging to the Parachlamydiaceae are obligate intracellular bacteria that infect Acanthamoeba, a free-living amoeba, and are a... -
A systematic review of the association between delayed appropriate therapy an...
Abstract Background Temporal relationships between the time to appropriate antibiotic therapy and outcomes are not well described. Methods A systematic literature review and... -
Study of serious adverse drug reactions using FDA-approved drug labeling and ...
Abstract Background Adverse Drug Reactions (ADRs) are of great public health concern. FDA-approved drug labeling summarizes ADRs of a drug product mainly in three sections,... -
A practical guide for probiotics applied to the case of antibiotic-associated...
Abstract Background Antibiotic-associated diarrhea (AAD) is a side-effect frequently associated with the use of broad spectrum antibiotics. Although a number of clinical studies... -
Clinical characteristics of the patients with bacteremia due to Moraxella cat...
Abstract Background Invasive diseases due to Moraxella catarrhalis are rare in children, even in immunocompromised hosts. Therefore, data regarding clinical characteristics and... -
Implementation fidelity of hospital based directly observed therapy for tuber...
Abstract Background Direct observed treatment (DOT) has been implemented in Bhutan since 1997 and currently, it is offered in various model of delivery including a combination... -
MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to fo...
Abstract Background Dendritic cells (DCs) are specialized first-line sensors of foreign materials invading the organism. These sentinel cells rely on pattern recognition... -
The WHO Safe Childbirth Checklist implementation: impact on the prescription ...
Abstract Background Preeclampsia is a relatively frequent condition during pregnancy and childbirth. The administration of magnesium sulphate as a prophylactic and treatment... -
A scoping review on the field validation and implementation of rapid diagnost...
Abstract Background Health personnel face challenges in diagnosing vector-borne and other diseases of poverty in urban settings. There is a need to know what rapid diagnostic... -
Risk factors for death among children 0–59 months of age with moderate-to-sev...
Abstract Background Despite major improvements in child survival rates, the number of deaths due to diarrhea remains unacceptably high. We aimed to describe diarrhea-associated... -
Ubiquitous giants: a plethora of giant viruses found in Brazil and Antarctica
Abstract Background Since the discovery of giant viruses infecting amoebae in 2003, many dogmas of virology have been revised and the search for these viruses has been...
