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Amorphous silica nanoparticles induce malignant transformation and tumorigene...
Rapid development and deployment of engineered nanomaterials, such as amorphous silica nanoparticles (SiNPs) in various commercial and biomedical applications have raised... -
Statin use in cancer survivors versus the general population: cohort study us...
Abstract Background Cancer survivors may be at increased risk of cardiovascular diseases, but little is known about whether prescribing guidelines for the primary prevention of... -
Effect of delayed misoprostol dosing interval for induction of labor: a retro...
Abstract Background Induction of labor occurs in greater than 22% of all pregnancies in the United States. Previous studies have shown that misoprostol is more effective for... -
A qualitative study on stakeholders’ views on the participation of pregnant w...
Abstract Background Bioethicists argue that inclusion of pregnant women in clinical research should be more routine to increase the evidence-base for pregnant women and... -
Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats...
Abstract Background Recurrent and persistent infections are known to affect airways of patients with Primary Immunodeficiency despite appropriate replacement immunoglobulin... -
Prevalence and profile of adverse drug reactions in high-risk pregnancy: a co...
Abstract Background Commonly used drugs in pregnant women include antihypertensives, hypoglycemic agents, analgesics, antimicrobials, antiemetics and antispasmodics but the use... -
Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrat...
Abstract Background Zyflamend, a blend of herbal extracts, effectively inhibits tumor growth using preclinical models of castrate-resistant prostate cancer mediated in part by... -
Complementary and alternative medicine use: Results from a descriptive study ...
Abstract Background The use of CAM by pregnant women is very popular in developed countries. The trend is increasing globally and lack of evidence of safety particularly when... -
Inhibition of Salmonella Typhimurium adhesion, invasion, and intracellular su...
Abstract Salmonella enterica serovar Typhimurium infects intestinal epithelia and macrophages, which is prevented by inhibiting adhesion and cell invasion. This study aimed to... -
Efficacy and safety of everolimus in combination with trastuzumab and paclita...
Abstract Background The current exploratory analysis was performed to evaluate the efficacy and safety of everolimus for treatment of human epidermal growth factor receptor... -
Topical application of Jaungo in atopic dermatitis patients: study protocol f...
Abstract Background Atopic dermatitis (AD) is a common pruritic inflammatory skin disease with increasing prevalence. It can manifest with many different clinical phenotypes;... -
ALternatives To prophylactic Antibiotics for the treatment of Recurrent urina...
Abstract Background At least half of all adult women will experience infective cystitis (urinary tract infection: UTI) at least once in their life and many suffer from repeated... -
Activated spinal astrocytes contribute to the later phase of carrageenan-indu...
Abstract Background Prostatodynia is the main symptom of chronic prostatitis and the main reason that patients go to the hospital for treatment. Although a variety of factors,... -
Minoxidil versus placebo in the treatment of arterial wall hypertrophy in chi...
Abstract Background Insufficient elastin synthesis leads to vascular complications and arterial hypertension in children with Williams-Beuren syndrome. Restoring sufficient... -
Which potential harms and benefits of using ginger in the management of nause...
Abstract Background Nausea and vomiting of pregnancy (NVP) affect approximately 80â 90% of the pregnant women. Ginger (Zingiber officinale Roscoe) is the most widely used... -
Six-month adherence to Statin use and subsequent risk of major adverse cardio...
Abstract Background The evidence of adherence to statin decreasing risk of major adverse cardiovascular events (MACEs) is still lack among patients discharged with acute... -
Patient-reported outcomes from a randomized phase II study of the deferasirox...
Abstract Background Adherence to long-term chelation therapy in transfusion-dependent patients is critical to prevent iron overload-related complications. Once-daily deferasirox... -
Effect of extra-amniotic Foley’s catheter and vaginal misoprostol versus vagi...
Abstract Background The safest, most effective and fastest combined approaches to induction of labor is unknown. In an open-label randomized clinical trial we evaluated the... -
Self-medication during pregnancy and associated factors among pregnant women ...
Abstract Objective The use of self-medications during pregnancy results in serious structural as well as functional adverse effects on mothers and unborn children. But little is... -
A mutation that blocks integrin α4β7 activation prevents adaptive immune-medi...
Abstract Background β7 integrins are responsible for the efficient recruitment of lymphocytes from the blood and their retention in gut-associated lymphoid tissues. Integrin...
