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Helios + Regulatory T cell frequencies are correlated with control of viral r...
Abstract Background The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation.... -
UK national clinical audit: management of pregnancies in women with HIV
Abstract Background The potential for HIV transmission between a pregnant woman and her unborn child was first recognized in 1982. Since then a complex package of measures to... -
Climate factors driven typhus group rickettsiosis incidence dynamics in Xishu...
Abstract Background Typhus group rickettsiosis (TGR), which is a neglected vector-borne infectious disease, including epidemic typhus and endemic typhus. We explored the lag... -
Estimating the cost-effectiveness of daclatasvir + sofosbuvir versus sofosbuv...
Abstract Background As treatments for chronic hepatitis C are moving away from interferon-containing regimens, the most appropriate allocation of resources to higher cost,... -
To evaluate the efficacy and safety of PLC in perimenopausal or postmenopausa...
Abstract Background Hot flashes are the most frequent symptoms of the menopause, with 10–20% of all postmenopausal women reporting nearly intolerable occurrences. Although... -
Burden of chronic kidney disease on the African continent: a systematic revie...
Abstract Background Accurate contemporary data on the burden of Chronic Kidney Disease (CKD) on the African continent are lacking. We determined the prevalence of CKD in adult... -
Community-onset sepsis and its public health burden: a systematic review
Abstract Background Sepsis is a life-threatening condition and major contributor to public health and economic burden in the industrialised world. The difficulties in accurate... -
Estimating the impact post randomization changes in staff behavior in infecti...
Abstract Background Randomized controlled trials (RCTs) of behavior-based interventions are particularly vulnerable to post-randomization changes between study arms. We assess... -
Clinical vignettes and global health considerations of infertility care in un...
Abstract The ability to receive standard of care for a diagnosis of infertility is a factor of oneâ s financial state and educational level, which are often correlated.... -
Healthcare utilization and direct costs of non-infectious comorbidities in HI...
Objective: To estimate the incremental healthcare utilization and costs associated with common non-infectious comorbid conditions among commercially and Medicaid-insured... -
Systematic literature review and meta-analysis of the efficacy of artemisinin...
Abstract Background There is no agreed standard method to assess the efficacy of anti-malarials for uncomplicated falciparum in pregnancy despite an increased risk of adverse... -
The WHO Safe Childbirth Checklist implementation: impact on the prescription ...
Abstract Background Preeclampsia is a relatively frequent condition during pregnancy and childbirth. The administration of magnesium sulphate as a prophylactic and treatment... -
Adverse obstetric and neonatal outcomes complicated by psychosis among pregna...
Abstract Background Adverse obstetric and neonatal outcomes among women with psychosis, particularly affective psychosis, has rarely been studied at the population level. We... -
Detection of lipoarabinomannan (LAM) in urine is an independent predictor of ...
Abstract Background Simple immune capture assays that detect mycobacterial lipoarabinomannan (LAM) antigen in urine are promising new tools for the diagnosis of HIV-associated... -
Respiratory virus-associated infections in HIV-infected adults admitted to th...
Abstract Introduction Acute respiratory failure is the main reason for admission to the intensive care unit (ICU) in HIV-infected adults. There is little data about the... -
Association between periodontal disease and mortality in people with CKD: a m...
Abstracts Background Periodontal disease occurs relatively prevalently in people with chronic kidney disease (CKD), but it remains indeterminate whether periodontal disease is... -
The present and future burden of previously treated advanced non-small cell l...
Abstract Background The burden of advanced non-small cell lung cancer (NSCLC) is not well understood, and the number of patients likely to receive treatment in Europe has not... -
Combined interventions to reduce HIV incidence in KwaZulu-Natal: a modelling ...
Abstract Background Combined prevention interventions, including early antiretroviral therapy initiation, may substantially reduce HIV incidence in hyperendemic settings. Our... -
Relation of multi-marker panel to incident chronic kidney disease and rapid k...
Abstract Background Few investigations have evaluated the incremental usefulness of multiple biomarkers representing varying physiological pathways for predicting risk of renal... -
Gender disparity in epidemiological trend of HIV/AIDS infection and treatment...
Abstract Background The HIV/AIDS epidemic has been fuelled by gender inequality and disparity resulted in violation of women reproductive right. The â feminizationâ of the...
