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Climate factors driven typhus group rickettsiosis incidence dynamics in Xishu...
Abstract Background Typhus group rickettsiosis (TGR), which is a neglected vector-borne infectious disease, including epidemic typhus and endemic typhus. We explored the lag... -
Using predicate and provenance information from a knowledge graph for drug ef...
Abstract Background Biomedical knowledge graphs have become important tools to computationally analyse the comprehensive body of biomedical knowledge. They represent knowledge... -
The potential role of infectious agents and pelvic inflammatory disease in ov...
Abstract Background The etiological cause of ovarian cancer is poorly understood. It has been theorized that bacterial or viral infection as well as pelvic inflammatory disease... -
Burden of chronic kidney disease on the African continent: a systematic revie...
Abstract Background Accurate contemporary data on the burden of Chronic Kidney Disease (CKD) on the African continent are lacking. We determined the prevalence of CKD in adult... -
Gene expression prediction using low-rank matrix completion
Abstract Background An exponential growth of high-throughput biological information and data has occurred in the past decade, supported by technologies, such as microarrays and... -
Erratum to: Expanded Quality Management Using Information Power (EQUIP): prot...
Erratum to: Expanded Quality Management Using Information Power (EQUIP): protocol for a quasi-experimental study to improve maternal and newborn health in Tanzania and Uganda -
Detection of lipoarabinomannan (LAM) in urine is an independent predictor of ...
Abstract Background Simple immune capture assays that detect mycobacterial lipoarabinomannan (LAM) antigen in urine are promising new tools for the diagnosis of HIV-associated... -
Association between periodontal disease and mortality in people with CKD: a m...
Abstracts Background Periodontal disease occurs relatively prevalently in people with chronic kidney disease (CKD), but it remains indeterminate whether periodontal disease is... -
Math for the Benefit of Society: A New MATLAB-Based Gen-Ed Course
Responding to a call for national reform of mathematical education, as well as a college-wide revision of general education (GE) requirements, we describe a new entry-level, GE... -
The present and future burden of previously treated advanced non-small cell l...
Abstract Background The burden of advanced non-small cell lung cancer (NSCLC) is not well understood, and the number of patients likely to receive treatment in Europe has not... -
Combined interventions to reduce HIV incidence in KwaZulu-Natal: a modelling ...
Abstract Background Combined prevention interventions, including early antiretroviral therapy initiation, may substantially reduce HIV incidence in hyperendemic settings. Our... -
Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin-based combin...
Abstract Background Activation of hypnozoites of vivax malaria causes multiple clinical relapses, which contribute to the Plasmodium vivax burden and continuing transmission.... -
Relation of multi-marker panel to incident chronic kidney disease and rapid k...
Abstract Background Few investigations have evaluated the incremental usefulness of multiple biomarkers representing varying physiological pathways for predicting risk of renal... -
Design of trials for interrupting the transmission of endemic pathogens
Abstract Background Many interventions against infectious diseases have geographically diffuse effects. This leads to contamination between arms in cluster-randomized trials... -
Use of biologically-based complementary medicine in breast and gynecological ...
Abstract Background Biologically-based complementary medicines (BB-CAM) including herbs and nutritional supplements are frequently taken by breast- and gynecological cancer... -
Outcomes of community-based differentiated models of multi-month dispensing o...
Abstract Background Current World Health Organization (WHO) guidelines recommend early initiation of HIV positive patients on antiretroviral therapy (ART) irrespective of their... -
Status of metered dose inhaler technique among patients with asthma and its e...
Abstract Objective In Asthma management, poor handling of inhalation devices and wrong inhalation technique are associated with decreased medication delivery and poor disease... -
Involvement of DPP9 in gene fusions in serous ovarian carcinoma
Abstract Background A fusion gene is a hybrid gene consisting of parts from two previously independent genes. Chromosomal rearrangements leading to gene breakage are frequent in... -
Mathematical models for devising the optimal Ebola virus disease eradication
Abstract Background The 2014â 2015 epidemic of Ebola virus disease (EVD) in West Africa defines an unprecedented health threat for human. Methods We construct a mathematical... -
Role of ethambutol and rifampicin in the treatment of Mycobacterium avium com...
Abstract Background A three-drug regimen (macrolide, ethambutol, and rifampicin) is recommended for the treatment of Mycobacterium avium complex pulmonary disease (MAC-PD)....
