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Selection bias in clinical stroke trials depending on ability to consent
Abstract Background Clinical trials are the hallmark of evidence-based medicine, but recruitment is often challenging, especially in stroke trials investigating patients not... -
Environmental and social determinants of population vulnerability to Zika vir...
Abstract Background Zika virus (ZIKV) spread rapidly in the Americas in 2015. Targeting effective public health interventions for inhabitants of, and travellers to and from,... -
Assessing core, e-learning, clinical and technology readiness to integrate te...
Abstract Background In developing countries like Uganda, there are shortages of health workers especially medical specialists. The referral process is frustrating to both... -
How best to structure interdisciplinary primary care teams: the study protoco...
Abstract Background Western publicly funded health care systems increasingly rely on interdisciplinary teams to support primary care delivery and management of chronic... -
Association of statin use and clinical outcomes in heart failure patients: a ...
Abstract Background The role of statins in patients with heart failure (HF) of different levels of left ventricular ejection fraction (LVEF) remains unclear especially in the... -
SARS-CoV-2 detection in the lower respiratory tract of invasively ventilated ...
Abstract Background Data on SARS-CoV-2 load in lower respiratory tract (LRT) are scarce. Our objectives were to describe the viral shedding and the viral load in LRT and to... -
Interventions for improved diabetes control and self-management among those e...
Abstract Background Diabetes is a chronic medical condition that requires patients to be actively engaged in intensive self-management to achieve optimal clinical outcomes.... -
Paediatric tuberculosis diagnosis using Mycobacterium tuberculosis real-time ...
Abstract Background Tuberculosis (TB) diagnosis in children is a major challenge with up to 94% of children with TB treated empirically in TB high-burden countries. Paediatric... -
Validation of genotype cluster investigations for Mycobacterium tuberculosis:...
Abstract Background Tracking the dissemination of specific Mycobacterium tuberculosis (Mtb) strains using genotyped Mtb isolates from tuberculosis patients is a routine public... -
The burden of laboratory-confirmed pertussis in low- and middle-income countr...
Abstract Background An effective vaccine against Bordetella pertussis was introduced into the Expanded Programme on Immunisation (EPI) by WHO in 1974, leading to a substantial... -
"I just have to take it" – patient safety in acute care: perspectives and exp...
Abstract Background Frequent hospitalizations and dependency on technology and providers place individuals with chronic kidney disease (CKD) at high risk for multiple safety... -
Opioid substitution treatment and heroin dependent adolescents: reductions in...
Abstract Background Opioid dependence is a major health concern across the world and does also occur in adolescents. While opioid substitution treatment (OST) has been...
