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Elevated TRIP13 drives the AKT/mTOR pathway to induce the progression of hepa...
Abstract Background ATPase associated with a variety of cellular activities (AAA ATPase) family members are closely linked to tumor formation and progression. However, their... -
Does pattern mixture modelling reduce bias due to informative attrition compa...
Abstract Background Informative attrition occurs when the reason participants drop out from a study is associated with the study... -
Assessing value in health care: using an interpretive classification system t...
Abstract Background Implementing adequate strategies to assess the value of health services plays a central role in the effort to deal with the financial pressures faced by... -
Deltopectoral flap revisited for reconstruction surgery in patients with adva...
Abstract Background We present the cases of 2 patients with invasive thyroid cancer, who underwent reconstructive surgery using a deltopectoral flap. Although the overall rate... -
Prevalence and incidence of atherosclerotic cardiovascular disease and its ri...
Abstract Background Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in Korea. According to a report of published by Statistics Korea in 2014,... -
Towards achieving semantic interoperability of clinical study data with FHIR
Abstract Background Observational clinical studies play a pivotal role in advancing medical knowledge and patient healthcare. To lessen the prohibitive costs of conducting these... -
Identifying potential causal effects of age at menarche: a Mendelian randomiz...
Abstract Background Age at menarche has been associated with various health outcomes. We aimed to identify potential causal effects of age at menarche on health-related traits... -
Plasma metabolites associated with arterial stiffness in patients with type 2...
Abstract Background Although an increased arterial stiffness has been associated with traditional coronary risk factors, the risk factors and pathology of arterial stiffness... -
Clinical exome sequencing in France and Quebec: what are the challenges? What...
Abstract Background The decreasing cost of next-generation sequencing technologies (NGS) has resulted in their increased use in research, and in the clinic. However, France and... -
Interventions in education to prevent STEM pipeline leakage
The so-called leaking STEM pipeline (dropout in STEM education) has been the subject of many studies. The large interest of scholars in plausible causes of this leakage has... -
Quantitative benefit-risk assessment of methylprednisolone in multiple sclero...
Abstract Background High-dose short-term methylprednisolone is the recommended treatment in the management of multiple sclerosis relapses, although it has been suggested that...
