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Concordance analysis of microarray studies identifies representative gene exp...
Abstract Background As the popularity of transcriptomic analysis has grown, the reported lack of concordance between different studies of the same condition has become a growing... -
Profiling of metalloprotease activities in cerebrospinal fluids of patients w...
Abstract Background Neoplastic invasion into leptomeninges and subarachnoid space, resulting in neoplastic meningitis (NM) is a fatal complication of advanced solid and... -
Hospital utilization rates following antipsychotic dose reduction in mood dis...
Abstract Background The relative benefits and risks of long-term maintenance treatment with antipsychotics have not been well studied in patients with bipolar disorder and major... -
TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers
Abstract Background Low frequency coding variants in TREM2 are associated with Alzheimer disease (AD) risk and cerebrospinal fluid (CSF) TREM2 protein levels are different... -
dedup_wf_001--072e09e2f3a4148cc75d8f03de4f00b4
Impaired semantic knowledge is a characteristic feature of some forms of frontotemporal dementia (FTD), particularly the sporadic disorder semantic dementia. Less is known about... -
Selective suppression of the JNK-MMP2/9 signal pathway by tetramethylpyrazine...
Abstract Background Activated astrocytes release matrix metalloproteinase-2/9 (MMP-2/9) to induce central sensitization and maintain neuropathic pain. However, the mechanisms... -
Endo-lysosomal dysregulations and late-onset Alzheimer’s disease: impact of g...
Abstract Increasing evidence supports that cellular dysregulations in the degradative routes contribute to the initiation and progression of neurodegenerative diseases,... -
Re-irradiation for recurrent glioma- the NCI experience in tumor control, OAR...
Abstract Purpose/objectives Despite mounting evidence for the use of re-irradiation (re-RT) in recurrent high grade glioma, optimal patient selection criteria for re-RT remain... -
A1 reactive astrocytes and a loss of TREM2 are associated with an early stage...
Abstract Background Cerebral amyloid angiopathy (CAA) is typified by the cerebrovascular deposition of amyloid. The mechanisms underlying the contribution of CAA to... -
Assessment of the underlying systems involved in standing balance: the additi...
Abstract Background Closed loop system identification (CLSIT) is a method to disentangle the contribution of underlying systems in standing balance. We investigated whether... -
Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia
Abstract Background Hypoxic pulmonary vasoconstriction (HPV) optimizes the match between ventilation and perfusion in the lung by reducing blood flow to poorly ventilated... -
Integral holography: white-light single-shot hologram acquisition
A new method for obtaining digital Fourier holograms, under spatially incoherent white-light illumination and in a single camera shot, is presented. Multiple projections of the... -
Using smartphones to decrease substance use via self-monitoring and recovery ...
Abstract Background Alcohol abuse, other substance use disorders, and risk behaviors associated with the human immunodeficiency virus (HIV) represent three of the top 10... -
Protective Effect of Intravitreal Administration of Exosomes Derived from Mes...
Purpose: Exosomes derived from human mesenchymal stem cells (hMSCs) cultured under hypoxic conditions contain proteins and growth factors that promote angiogenesis. This study... -
Epidemiological association between multiple chemical sensitivity and birth b...
Abstract Introduction Multiple chemical sensitivity (MCS) is characterized by recurrent nonspecific symptoms that are attributed to exposure to trace levels of environmental... -
Randomized controlled studies on the efficacy of antiarthritic agents in inhi...
Abstract Background As an initial step in the development of a local therapeutic to treat osteoarthritis (OA), a number of agents were tested for their ability to block... -
Cocaine-mediated induction of microglial activation involves the ER stress-TL...
Abstract Background Neuroinflammation associated with advanced human immunodeficiency virus (HIV)-1 infection is often exacerbated by chronic cocaine abuse. Cocaine exposure has...
