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Availability, accessibility and delivery to patients of the 28 orphan medicin...
Abstract Background The European Medicine Agency granted marketing approval to 164 orphan medicinal products for rare diseases, among which 28 products intended for the... -
Effectiveness of training in evidence-based medicine skills for healthcare pr...
Abstract Background Basic skills in evidence-based medicine (EbM) are indispensable for healthcare professionals to promote consumer-centred, evidence-based treatment. EbM... -
Systematic review of outcome domains and instruments used in clinical trials ...
Abstract Background There is no evidence-based guidance to facilitate design decisions for confirmatory trials or systematic reviews investigating treatment efficacy for adults... -
Cost of inappropriate antimicrobial use for upper respiratory infection in Japan
Abstract Background Antibiotics are often prescribed inappropriately to patients with upper respiratory infection (URI) in ambulatory care settings; however, the economic burden... -
A systematic literature review of reviews on techniques for physical activity...
Abstract The links between increased participation in Physical Activity (PA) and improvements in health are well established. As this body of evidence has grown, so too has the... -
Physical activity and the prevention, reduction, and treatment of alcohol and...
Abstract Background Alcohol and substance use results in significant human and economic cost globally and is associated with economic costs of ÂŁ21 billion and ÂŁ15billion... -
Work-related adverse events leaving their mark: a cross-sectional study among...
Abstract Background Health care professionals who are frequently coping with traumatic events have an increased risk of developing a posttraumatic stress disorder. Research... -
Impact of faculty development programme on self-efficacy, competency and atti...
Abstract Background Soon after Bhutan’s first medical university was established in 2012, Faculty Development Programmes (FDPs) were adopted for efficient delivery of... -
Variability of Uncrossmatched Blood Use by Helicopter EMS Programs in the Uni...
Study Objective: Some helicopter emergency medical services (HEMS) maintain an independent supply of blood for use during transport, although practice is variable and not well... -
Combination of Ranibizumab with macular laser for macular edema secondary to ...
Abstract Background It is not clear whether macular laser combined with anti-vascular endothelial growth factor (VEGF) can reduce the number of anti-VEGF injections in the... -
Association between objectively measured physical activity and body mass inde...
Abstract Background The relationship between the combination of physical activity (PA) and body mass index (BMI) with low back pain (LBP) is unclear. The present study offers a... -
Changing the Antibiotic Prescribing of general practice registrars: the ChAP ...
Abstract Background Australian General Practitioners (GPs) are generous prescribers of antibiotics, prompting concerns including increasing antimicrobial resistance in the... -
Influencing factors of physicians’ prescription behavior in selecting essenti...
Abstract Background To explore the key factors affecting prescription practices of essential medicines in Chinese county hospital. National essential medicine policy (NEMP)... -
Effect of smoking status on lung function, patient-reported outcomes, and saf...
Abstract Background Smoking is a major risk factor for COPD and may impact the efficacy of COPD treatments; however, a large proportion of COPD patients continue to smoke... -
Possible beneficial association between renin-angiotensin-aldosterone-system ...
Abstract Background Although immunoglobulin A nephropathy (IgAN) is associated with an increased risk of renal allograft failure, evidences for its treatment, including... -
Experimental study on the effects of isoflurane with and without remifentanil...
Abstract Background Heart rate variability (HRV) provides information about autonomic nervous system (ANS) activity and is therefore a possible tool with which to assess... -
Amorphous silica nanoparticles induce malignant transformation and tumorigene...
Rapid development and deployment of engineered nanomaterials, such as amorphous silica nanoparticles (SiNPs) in various commercial and biomedical applications have raised... -
Prenatal alcohol exposure and infant gross motor development: a prospective c...
Abstract Background Maternal alcohol consumption in pregnancy may have adverse effects on child gross motor (GM) development. There have been few human studies on this topic,... -
Measurement resources for dissemination and implementation research in health
Abstract Background A 2-day consensus working meeting, hosted by the United States National Institutes of Health and the Veterans Administration, focused on issues related to... -
Impact of sunlight exposure on the residual efficacy of biolarvicides Bacillu...
Abstract Background Biotic and abiotic factors have been reported to affect the larvicidal efficacy of Bacillus thuringiensis israelensis (Bti) and Bacillus sphaericus (Bs),...
