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Cocaine-mediated induction of microglial activation involves the ER stress-TL...
Abstract Background Neuroinflammation associated with advanced human immunodeficiency virus (HIV)-1 infection is often exacerbated by chronic cocaine abuse. Cocaine exposure has... -
Healthcare cost comparison analysis of nivolumab in combination with ipilimum...
Abstract Background Monoclonal antibodies targeting the cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) (e.g., ipilimumab [IPI]) and the programmed cell death-1 (PD1)... -
Neuropsychological profiles of adult bipolar disorder patients with and witho...
Abstract Background Comorbid attention-deficit/hyperactivity disorder (ADHD) is common in bipolar disorder and associated with worse outcomes. Cognitive testing might be a tool... -
Microglial depletion and repopulation in brain slice culture normalizes sensi...
Abstract Background Microglia are critical mediators of neuroimmune pathology across multiple neurologic disorders. Microglia can be persistently activated or “primed” by... -
A case report of one vasovagal syncope patient with third-degree atrioventric...
Abstract Background Vasovagal syncope (VVS) is common in children and significantly affects their quality of life. To our knowledge, this the first case report of SCN5A gene... -
Association of statin use and clinical outcomes in heart failure patients: a ...
Abstract Background The role of statins in patients with heart failure (HF) of different levels of left ventricular ejection fraction (LVEF) remains unclear especially in the... -
A p53/TIAF1/WWOX triad exerts cancer suppression but may cause brain protein ...
Abstract Background Tumor suppressor WWOX physically binds p53 and TIAF1 and together induces apoptosis and tumor suppression. To understand the molecular action, here we...
