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Ethics of research on stem cells and regenerative medicine: ethical guideline...
Abstract Background Regenerative medicine plays a major role in biomedicine, and given the ever-expanding boundaries of this knowledge, numerous ethical considerations have been... -
Adverse childhood experiences and health-related quality of life in adulthood...
Abstract Background Adverse childhood experiences (ACE) have been previously linked to quality of life, health conditions, and life expectancy in adulthood. Less is known about... -
Coexisting ovarian and tubal pregnancies on opposite sides after intrauterine...
Abstract Background Ovarian pregnancy is very rare, and contralateral tubal pregnancy coexisting with ovarian pregnancy must be even rarer. Case presentation A 33-year-old... -
Childhood ADHD and treatment outcome: the role of maternal functioning
Abstract Background Relatively little is known about the role of maternal functioning in terms of attention deficit hyperactivity disorder (ADHD) symptoms, attachment style and... -
A review on the salt bridge ASP177-ARG163 (O–N) of wild-type rabbit prion pro...
A review on the salt bridge ASP177-ARG163 (O–N) of wild-type rabbit prion protein -
Clinical characteristics and outcomes of immune checkpoint inhibitor-induced ...
Abstract Background Immune checkpoint inhibitor (ICI)-induced pancreatic injury (ICIPI) is not well documented in the literature. We aimed to describe the clinical... -
Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
Abstract Background CpG islands (CGIs) are interspersed DNA sequences that have unusually high CpG ratios and GC contents. CGIs are typically located in the promoter of... -
BCL2 overexpression: clinical implication and biological insights in acute my...
Abstract Background BCL2 protein inhibitor venetoclax (ABT-199) has been authorized by Food and Drug Administration for relapsed/refractory chronic lymphoid leukemia with 17p... -
The effect of dexmedetomidine on vasopressor requirements in patients with se...
Abstract Background Septic shock is associated with decreased vasopressor responsiveness. Experimental data suggest that central alpha2-agonists like dexmedetomidine (DEX)... -
E-cigarettes and smoking cessation: a prospective study of a national sample ...
Abstract Background Smoking during pregnancy has adverse health consequences for the mother and fetus. E-cigarettes could aid with smoking cessation but there is limited... -
Retinal-image quality and contrast sensitivity function in eyes with epiretin...
Abstract Background To investigate the effect of idiopathic epiretinal membrane (ERM) on the retinal-image quality and psychophysical contrast sensitivity function (CSF).... -
Murine sepsis phenotypes and differential treatment effects in a randomized t...
Abstract Background Clinical and biologic phenotypes of sepsis are proposed in human studies, yet it is unknown whether prognostic or drug response phenotypes are present in... -
Sample size and number of outcome measures of veterinary randomised controlle...
Abstract Background Randomised controlled trials (RCTs) are a key component of the veterinary evidence base. Sample sizes and defined outcome measures are crucial components of... -
Medication use during pregnancy, gestational age and date of delivery: agreem...
Abstract Background Health databases are a promising resource for epidemiological studies on medications safety during pregnancy. The reliability of information on medications... -
On the dynamics of Airy beams in nonlinear media with nonlinear losses
We investigate on the nonlinear dynamics of Airy beams in a regime where nonlinear losses due to multi-photon absorption are significant. We identify the nonlinear Airy beam... -
A prospective pilotstudy comparing the anesthetic effects of an alpha-2 agoni...
Abstract Background To examine the response to an α2receptor agonist used as a sedative for patients using long-term selective α1 blockers. Methods Sixty-nine consecutive... -
Early maternal weight gain as a risk factor for SGA in pregnancies with hyper...
Abstract Background Inadequate maternal weight gain increases the risk of small-for-gestational age (SGA) infants. Women with hyperemesis gravidarum (HG) are at risk of... -
Inhaled AP301 for treatment of pulmonary edema in mechanically ventilated pat...
Abstract Background High-permeability pulmonary edema is a hallmark of acute respiratory distress syndrome (ARDS) and is frequently accompanied by impaired alveolar fluid... -
Association between pre-pregnancy body weight and dietary pattern with large-...
Abstract Background Both obesity and gestational diabetes (GDM) are associated with adverse outcomes. Diet during pregnancy impacts weight gain and fetal growth. Therefore, we... -
Efficacy and safety of administering oral misoprostol by titration compared t...
Abstract Background Among the various methods available, the administration of prostaglandins is the most effective for inducing labour in women with an unfavourable cervix....