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Surgical referral coordination from a first-level hospital: a prospective cas...
Background: Patients in isolated rural communities typically lack access to surgical care. It is not feasible for most rural first-level hospitals to provide a full suite of... -
Advice from the health insurer as a channelling strategy: a natural experimen...
Background In a health care system based on managed competition it is important that health insurers are able to channel their enrolees to preferred care providers. However,... -
GDF-15 plasma levels in chronic obstructive pulmonary disease are associated ...
Background Growth differentiation factor-15 (GDF-15), a cytokine associated with cardiovascular mortality, increases during chronic obstructive pulmonary disease (COPD)... -
Heterogeneous burden of lung disease in smokers with borderline airflow obstr...
Background The identification of smoking-related lung disease in current and former smokers with normal FEV1 is complex, leading to debate regarding using a ratio of forced... -
Cost of HPV screening at community health campaigns (CHCs) and health clinics...
Background Cervical cancer is the most frequent neoplasm among Kenyan women, with 4800 diagnoses and 2400 deaths per year. One reason is an extremely low rate of screening... -
The effect of postoperative gemcitabine on overall survival in patients with ...
Background: Adjuvant chemotherapy following curative resection is the standard treatment for pancreatic adenocarcinoma (PC). Randomized clinical trials using gemcitabine have... -
HERMIONE: a randomized Phase 2 trial of MM-302 plus trastuzumab versus chemot...
Background Human epidermal growth factor receptor 2 (HER2)-positive breast cancer is a particularly aggressive form of the disease, and ultimately progresses in patients with... -
A prebiotic intervention study in children with autism spectrum disorders (ASDs)
Background Different dietary approaches, such as gluten and casein free diets, or the use of probiotics and prebiotics have been suggested in autistic spectrum disorders in... -
From erasure to opportunity: a qualitative study of the experiences of transg...
Background Some transgender men retain their uterus, get pregnant, and give birth. However, societal attitudes about gender have erected barriers to openly being pregnant and... -
Effectiveness of the settings-based intervention Shaping the Social on preven...
Background Lack of formal education is an important social determinant of health inequality and represents a public health problem. School dropout is particularly common in... -
Beclomethasone dipropionate and formoterol fumarate synergistically interact ...
Background Corticosteroids increase the expression of β2-adrenoceptors (β2-ARs) and protect them against down-regulation. Conversely, β2-AR agonists improve the... -
Associations between degrees of task delegation and job satisfaction of gener...
Background In recent years, the healthcare system in the western world has undergone a structural development caused by changes in demography and pattern of disease. In order to... -
Cilostazol induced migraine does not respond to sumatriptan in a double blind...
Background Cilostazol is an inhibitor of phosphodiesterase 3 and thus causes accumulation of cAMP. It induces migraine-like attacks in migraine patients. Whether the cilostazol... -
Bisphenol a increases risk for presumed non-alcoholic fatty liver disease in ...
Background Bisphenol-A (BPA) is a ubiquitous chemical and recognized endocrine disruptor associated with obesity and related disorders. We explored the association between BPA... -
Language-concordant automated telephone queries to assess medication adherenc...
Background Clinicians have difficulty accurately assessing medication non-adherence within chronic disease care settings. Health information technology (HIT) could offer novel... -
Validation of the Jefferson Scale of Physician Empathy in Spanish medical stu...
Background The Jefferson Scale of Physician Empathy is the most widely used instrument to measure empathy in the doctor-patient relationship. This work pursued cultural... -
N-acetylcysteine exposure is associated with improved survival in anti-nuclea...
Background Mortality is similarly high among individuals with usual interstitial pneumonia (UIP) due to idiopathic pulmonary fibrosis (IPF) and interstitial pneumonia with... -
Epidemiology of non-steroidal antiinflammatory drugs consumption in Spain. Th...
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used despite their risk of gastrointestinal bleeding or cardiovascular events. We report the profile of people taking... -
Combined cognitive and vocational interventions after mild to moderate trauma...
Background A considerable proportion of patients with mild to moderate traumatic brain injury (TBI) experience long-lasting somatic, cognitive, and emotional... -
Natalizumab treatment reduces L-selectin (CD62L) in CD4+ T cells
Background The purpose of this research was to validate the low expression of L-selectin (CD62L) in natalizumab (NTZ)-treated patients. CD62L is involved in rolling and...
