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Comparative effectiveness of abatacept versus tocilizumab in rheumatoid arthr...
Abstract Background We compared the effectiveness of abatacept (ABA) vs tocilizumab (TCA) in tumor necrosis factor inhibitor (TNFi) experienced patients. Methods We identified... -
Macrophage Migration Inhibitory Factor (MIF) Enzymatic Activity and Lung Cancer
Abstract The cytokine macrophage migration inhibitory factor (MIF) possesses unique tautomerase enzymatic activity, which contributes to the biological functional activity of... -
Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transiti...
Abstract Background Multi-walled carbon nanotubes (MWCNT) are currently under intense toxicological investigation due to concern on their potential health effects. Current in... -
Phase I study of samalizumab in chronic lymphocytic leukemia and multiple mye...
Abstract Purpose Samalizumab is a novel recombinant humanized monoclonal antibody that targets CD200, an immunoregulatory cell surface member of the immunoglobulin superfamily... -
The potassium channel KCa3.1 constitutes a pharmacological target for astrogl...
Abstract Background Reactive astrogliosis is one of the significantly pathological features in ischemic stroke accompanied with changes in gene expression, morphology, and... -
Exploring differences in the use of the statin choice decision aid and diabet...
Abstract Background Shared decision making is essential to patient centered care, but can be difficult for busy clinicians to implement into practice. Tools have been developed... -
Do Cochrane summaries help student midwives understand the findings of Cochra...
Abstract Background Abstracts and plain language summaries (PLS) are often the first, and sometimes the only, point of contact between readers and systematic reviews. It is... -
The smoking cessation in pregnancy incentives trial (CPIT): study protocol fo...
Abstract Background Eighty per cent of UK women have at least one baby, making pregnancy an opportunity to help women stop smoking before their health is irreparably... -
Clinical guidelines for the management of treatment-resistant depression: Fre...
Abstract Background Clear guidance for successive antidepressant pharmacological treatments for non-responders in major depression is not well established. Method Based on the... -
Efficacy of acupuncture in the prevention and treatment of chemotherapy-induc...
Abstract Background Chemotherapy-induced nausea and vomiting (CINV) is a common and distressing side effect. We conducted this clinical trial to compare the effectiveness of... -
Concurrent chemoradiotherapy with weekly docetaxel versus cisplatin in the tr...
Abstract Background Promising efficacy and manageable toxicity of docetaxel-based concurrent chemoradiotherapy (CCRT) were reported in head and neck cancer. In addition, the... -
Effect of different delivery modes on the short-term strength of the pelvic f...
Abstract Background To investigate the effect of different delivery modes and related obstetric factors on the short-term strength of the pelvic floor muscle after delivery in... -
Blood pressure self-monitoring in pregnancy: examining feasibility in a prosp...
Abstract Background Raised blood pressure (BP) affects approximately 10% of pregnancies worldwide, and a high proportion of affected women develop pre-eclampsia. This study... -
Effect of delayed misoprostol dosing interval for induction of labor: a retro...
Abstract Background Induction of labor occurs in greater than 22% of all pregnancies in the United States. Previous studies have shown that misoprostol is more effective for... -
Development of a Core Outcome Set for Studies on Obesity in Pregnant Patients...
Abstract Background Maternal obesity is a risk factor for adverse maternal, fetal, and neonatal events. Numerous clinical trials are currently exploring the effectiveness of... -
Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye dr...
Abstract Background To determine the effect of various factors to the preservation rate of the conjunctival layer borderlines of glaucomatous eyes treated with anti-glaucoma eye... -
Co-activator candidate interactions for orphan nuclear receptor NR2E1
Abstract Background NR2E1 (Tlx) is an orphan nuclear receptor that regulates the maintenance and self-renewal of neural stem cells, and promotes tumourigenesis. Nr2e1-null mice... -
Relative efficacy of topical non-steroidal anti-inflammatory drugs and topica...
Abstract Background Pain is the most troubling issue to patients with osteoarthritis (OA), yet current pharmacological treatments offer only small-to-moderate pain reduction.... -
Will savings from biosimilars offset increased costs related to dose escalati...
Abstract Introduction Biosimilar infliximab has the potential for appreciable cost savings compared to its reference biologic, but dose escalation is common and increases costs.... -
Development of a core outcome set for amblyopia, strabismus and ocular motili...
Abstract Background Core Outcome Sets (COS) are defined as the minimum sets of outcomes that should be measured and reported in all randomised controlled trials to facilitate...
