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Proangiogenic alginate-g-pyrrole hydrogel with decoupled control of mechanica...
Abstract Background An electrically conductive hydrogel has emerged to regulate cellular secretion activities with electrical stimulation. However, the electrical conductivity... -
Enhancement of docosahexaenoic acid production by overexpression of ATP-citra...
Abstract Background Docosahexaenoic acid (DHA) is an important omega-3 long-chain polyunsaturated fatty acid that has a variety of physiological functions for infant development... -
The impact of RNA extraction method on accurate RNA sequencing from formalin-...
Abstract Background Utilization of RNA sequencing methods to measure gene expression from archival formalin-fixed paraffin-embedded (FFPE) tumor samples in translational... -
Additional file 5: of The prominent alteration in transcriptome and metabolom...
Table S5. The complete list of detected amino acids in control and VB1-treated samples. (XLSX 23 kb) -
The acid-sensing ion channel, ASIC2, promotes invasion and metastasis of colo...
Abstract Background The tumor acidic microenvironment, a common biochemical event in solid tumors, offers evolutional advantage for tumors cells and even enhances their... -
Extracellular production of the engineered thermostable protease pernisine fr...
Abstract Background The thermostable serine protease pernisine originates from the hyperthermophilic Archaeaon Aeropyrum pernix and has valuable industrial applications. Due to... -
Visualization of activity-regulated BDNF expression in the living mouse brain...
Abstract Altered levels of brain-derived neurotrophic factor (BDNF) have been reported in neurologically diseased human brains. Therefore, it is important to understand how the... -
Evaluation of human primary intestinal monolayers for drug metabolizing capab...
Abstract Background The intestinal epithelium is a major site of drug metabolism in the human body, possessing enterocytes that house brush border enzymes and phase I and II... -
NIH workshop report on the trans-agency blood–brain interface workshop 2016: ...
Abstract A trans-agency workshop on the blood–brain interface (BBI), sponsored by the National Heart, Lung and Blood Institute, the National Cancer Institute and the Combat... -
Association of ACE2 polymorphisms with susceptibility to essential hypertensi...
Abstract Background Cardiovascular benefits by reversing environmental risks factors for essential hypertension (EH) and dyslipidemia could be weaken by high genetic risk. We... -
High-level extracellular protein production in Bacillus subtilis using an opt...
Abstract Background We recently constructed a Bacillus subtilis strain (CCTCC M 2016536) from which we had deleted the srfC, spoIIAC, nprE, aprE and amyE genes. This strain is... -
Vitamin D receptor expression in invasive breast tumors and breast cancer sur...
Abstract Background Vitamin D has been suggested to prevent and improve the prognosis of several cancers, including breast cancer. We have previously shown a U-shaped... -
Developmental basis for intestinal barrier against the toxicity of graphene o...
Abstract Background Intestinal barrier is crucial for animals against translocation of engineered nanomaterials (ENMs) into secondary targeted organs. However, the molecular...
