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TREatment of ATopic eczema (TREAT) Registry Taskforce: protocol for an intern...
Abstract Background Patients with moderate-to-severe atopic eczema (AE) often require photo- or systemic immunomodulatory therapies to induce disease remission and maintain... -
Etoposide induces cell death via mitochondrial-dependent actions of p53
Abstract Background Etoposide has been used clinically in cancer treatment, as well as in numerous research studies, for many years. However, there is incomplete information... -
Achieving Self-Directed Integrated Cancer Aftercare (ASICA) in melanoma: prot...
Abstract Background Melanoma is common; 15,906 people in the UK were diagnosed with melanoma in 2015 and incidence has increased fivefold in 30 years. Melanoma affects old and... -
A randomised clinical trial of a metaphylactic treatment with tildipirosin fo...
Abstract Background Bovine respiratory disease (BRD) is a major problem in veal calf rearing units. The objective of this randomised clinical trial was to assess the... -
Ultrasound findings in critical care patients: the "liver sign" and other abn...
Abstract In critical care patients, point of care abdominal ultrasound examination, although it has been practiced for over 30 years, is not as widespread as its cardiac or... -
Pathogen-regulated genes in wheat isogenic lines differing in resistance to b...
Abstract Background Inoculation of wheat plants with Puccinia triticina (Pt) spores activates a wide range of host responses. Compatible Pt interaction with susceptible Thatcher... -
Novel strong promoter of antimicrobial peptides gene pro-SmAMP2 from chickwee...
Abstract Background In a previous study we found that in chickweed the expression level of the pro-SmAMP2 gene was comparable or even higher to that of the β-actin gene. This... -
Comparative population genomics reveals genetic divergence and selection in l...
Abstract Background Lotus (Nelumbo nucifera) is an aquatic plant with important agronomic, horticulture, art and religion values. It was the basal eudicot species occupying a... -
Effects of thiamine on vasopressor requirements in patients with septic shock...
Abstract Background Thiamine, an essential vitamin for aerobic metabolism and glutathione cycling, may decrease the effects of critical illnesses. The objective of this study... -
Complement activating ABO anti-A IgM/IgG act synergistically to cause erythro...
Abstract Background Typically minor ABO incompatible platelet products are transfused without any incident, yet serious hemolytic transfusion reactions occur. To mitigate these... -
High-throughput transcriptomics reveals common and strain-specific responses ...
Abstract Background Mycobacterium abscessus (MAB) is an emerging pathogen causing pulmonary infections in those with inflammatory lung disorders, such as Cystic Fibrosis (CF),... -
Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuat...
Abstract Background Chronic pro-inflammatory signaling propagates damage to neural tissue and affects the rate of disease progression. Increased activation of Toll-like... -
Widespread activation of antisense transcription of the host genome during he...
Abstract Background Herpesviruses can infect a wide range of animal species. Herpes simplex virus 1 (HSV-1) is one of the eight herpesviruses that can infect humans and is... -
FoxO3 regulates hepatic triglyceride metabolism via modulation of the express...
Abstract Background Excessive intrahepatic lipid accumulation is the major characteristic of nonalcoholic fatty liver disease (NAFLD). We sought to identify the mechanisms... -
Hospital mortality in acute coronary syndrome: adjustment of GRACE score by D...
Abstract Backgroud To assess the value of D-dimer and its combination with The Global Registry of Acute Coronary Events (GRACE) score in predicting in-hospital mortality in... -
Number attraction affects reanalysis in sentence processing
Many studies have shown evidence for number attraction effects in production. Recent cross-linguistic findings suggest that number attraction can also affect comprehension of... -
Mutational signatures: experimental design and analytical framework
Abstract Mutational signatures provide a powerful alternative for understanding the pathophysiology of cancer. Currently, experimental efforts aimed at validating and... -
A self-marker-like protein governs hemocyte allorecognition in Halocynthia ro...
Abstract Background Self-incompatibility, fusion/non-fusion reactions, and contact reactions (CRs) have all been identified as allorecognition phenomena in ascidians. CR is a... -
A novel Sugarcane bacilliform virus promoter confers gene expression preferen...
Abstract Background Saccharum species such as sugarcane and energy cane are key players in the expanding bioeconomy for sugars, bioenergy, and production of high-value proteins....
