-
Two-Step Metal-Mediated Transformation of Isoxazolidine-5-spirocyclopropanes ...
The two-step metal-catalyzed overall transformation of isoxazolidine-5-spirocyclopropanes into the corresponding dihydro- and tetrahydropyridones is described. The first step is... -
r37980778c78--f80faaf02c75a0c2e64e04befa186901
14β-4′-Chlorocinnamoylaminodihydronormorphinone (2a), and analogues, are selective pseudoirreversible antagonists of the μ opioid receptor (MOR). The preparation of analogues... -
dedup_wf_001--b632e5dfbec11ea43bb3c98ce56c6c9e
Langkah dan program untuk memperkokoh ideologi negara berbasis kearifan lokal adalah (1) melakukan mapping identitas lokal (local identity mapping), (2) internalisasi dan... -
From a Data Archive to Data Science: Supporting Current Research
“Reports of our death have been greatly exaggerated,” says the UCLA Social Science Data Archive. It’s true: the SSDA is not the same as it always was, and that is a success... -
Design of Potent Inhibitors for Human Brain Memapsin 2 (β-Secretase)
Design of Potent Inhibitors for Human Brain Memapsin 2 (β-Secretase) -
Oxidation of [Ru(NH<sub>3</sub>)<sub>5</sub>isn](BF<sub>4</sub>)<sub>2</sub> ...
UV−vis stopped-flow studies of the reaction of [Ru(NH3)5isn]2+ (isn = isonicotinamide) with excess HOCl at 25 °C demonstrate that it proceeds in two time-resolved steps. In the... -
CESSDA Webinar: Data Discovery
Slides from CESSDA Webinar on Data Discovery Data discovery is a crucial stage in the research process, especially in the social sciences and humanities as many valuable... -
r37980778c78--d180a70ef5bbec57c3e0030894fbd772
The reverse aromatic Cope rearrangement of 2-allyl-3-alkylideneindolines obtained by Horner−Wadsworth−Emmons olefination of 2-allylindolin-3-ones was performed. When... -
Dramatic Red-Shifted Fluorescence of [2.2]Paracyclophanes with Peripheral Sub...
A bridge-substituted [2.2]paracyclophane obtained from the organic solid state exhibits a dramatic red shift in fluorescence relative to [2.2]paracyclophane. A further red shift... -
The Transition to Open Science
Presentation from Frank Miedema in the Research Assessment panel at the Open Science FAIR 2019 (Porto, 16-17 September 2019). -
Research and education of wood pasture and ancient trees - Fáslegelők és ősfá...
Bogyiszlón a helyi általános iskola tanári karával és diákjaival, valamint helyi lakosok segítségével a fás legelőkről, őstölgyekről és pásztorvilágról szóló oktatási és... -
dedup_wf_001--9525b785d9b7f982e1f05c2f89de6c3b
Open Data und FAIR Data sind mittlerweile schimmernde Begriffe in der Wissenschaft. Im Sinne einer gemeinsamen Verständnisgrundlage soll in einem ersten Teil versucht werden,... -
r37980778c78--85cf15f6b7c878a47372001852fdcdbd
The ring opening reactions of fused cyclobutenes have been the subject of mechanistic debate for decades. Some reports have been published recently suggesting that, in some... -
r37980778c78--926c4ccb216886b66dc789b4cd79eddd
On treatment with 1 equiv of [Ph3C][B(C6F5)4], the scandium half-sandwich bis(alkyl) complex (C5Me4SiMe3)Sc(CH2SiMe3)2(THF) showed extremely high activity (up to 1.36 × 104 kg... -
r37980778c78--78da9eeaaad87091549a3451117a88ff
The effect of three in-plane (bond length alternation, bond length elongation, and clamping) and three out-of-plane deformations (boatlike, chairlike, and pyramidalization) on... -
First Synthesis of Isotactic Poly(9-alkyl<sub>1</sub>-9-alkyl<sub>2</sub>fluo...
Nonsymmetrically substituted chiral 9-alkyl1-9-alkyl2fluorene monomers of the AB type allow for their directed, stereoregular aryl−aryl cross-coupling after Suzuki leading to... -
dedup_wf_001--914a152bfc2a63dde7a2d9b6c9caba55
Presentation of various aspects of open science - categorized under 'open to participation', 'open to (re)use' and 'open to the world'. We provide this in static PNG and PDF... -
dedup_wf_001--b6c25903e385a6b8115f3afbb8206fae
Keynote talk at the Open Science Fair 2019, Porto, Portugal. Perhaps the most sincere and heart felt talk I have ever given about Open Science. I talk about things like... -
r37980778c78--f3a197b68a05abeefac70ede7861a6b2
This report describes recently discovered novel allosteric modulators of metabotropic glutamate2 (mGlu2) receptors. These pyridylmethylsulfonamides (e.g., 3) potentiate...
