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r37980778c78--4b8428408f24c08e392fd04bdc457ce8
The first uncatalyzed, diastereoselective vinylogous Mukaiyama aldol reaction is reported, between pyrrole/furan-based dienoxy silanes and aromatic aldehydes on salty... -
r37980778c78--e6e23c7867f9f8a422650bb13b55c841
Acetone precipitation is a common method for precipitation and concentration of proteins. We show here that a trace amount of residual acetone in the precipitated protein, can,... -
r37980778c78--b646c65239b500460d109f90f8ab026c
The total synthesis of the diterpene kellermanoldione 1 is reported. Stepwise [4 + 2] cycloaddition of the ketal diene 8 and the allenoate 3 afforded the exo adduct 10x as the... -
Multiplexed Sandwich Immunoassays using Electrochemiluminescence Imaging Reso...
A new class of bead-based microarray that uses electrogenerated chemiluminescence (ECL) as a readout mechanism to detect multiple antigens simultaneously is presented. This... -
r37980778c78--a37d79ea99c8768ca2a7b0f2603b6b02
A series of 3,6-disubstituted carbazole and 1,3,5-trisubstituted benzene derivatives incorporating thienyl aromatic (phenyl, fluorenyl, and carbazolyl) conjugation and... -
Dual-Vessel Integrated Microwave Sample Decomposition and Digest Evaporation ...
A dual-vessel apparatus using closed-vessel microwave sample preparation is designed. A protocol that includes in situ reagent purification, sample decomposition, and digest... -
r37980778c78--bb188a346e4d78d6ddba0f20eaca093a
A versatile synthetic route to potentially useful fused-ring [1,2,4]thiadiazole scaffolds (e.g., 7a and 10b) via exchange reactions of the precursor [1,2,4]thiadiazol-3-(2H)one... -
r37980778c78--1b7126077cba5fa4d30974e237410b0b
Novel 5-cyclic amine-3-arylsulfonylindazoles were prepared, and several analogues within this class have been identified as high-affinity 5-HT6 receptor ligands with improved... -
Synthesis of (+)-Complanadine A, an Inducer of Neurotrophic Factor Excretion
A total synthesis of the Lycopodium alkaloid (+)-complanadine A is described. Complanadine A has been shown to induce the secretion of neurotrophic factors from 1321N1 cells,... -
Enantioselective Direct Aza Hetero-Diels−Alder Reaction Catalyzed by Chiral B...
The first chiral Brønsted acid-catalyzed asymmetric direct aza hetero-Diels−Alder reaction has been described. The phosphoric acids, prepared from binol and H8-binol... -
Activation of p300 Histone Acetyltransferase by Small Molecules Altering Enzy...
Reversible acetylation of nucleosomal histones and nonhistone proteins play pivotal roles in the regulation of all the DNA templated phenomenon. Dysfunction of the enzymes... -
r37980778c78--47ed907d78f439f2725ecca139e14824
The reaction of the ketene acetal triflates 9a−e and a zinc homoenolate 10 in the presence of a catalytic amount of Pd(PPh3)4 gave the enol ethers 11a−e in good yields. The... -
r37980778c78--96219b3ba67495a89aa728b76185d81c
The first total syntheses of (+)-trienomycins A and F, representative members of a new class of cytotoxic ansamycin antibiotics, have been achieved. Key features of the unified... -
Role of Lysine-256 in <i>Citrobacter freundii</i> Tyrosine Phenol-lyase in Mo...
Tyrosine phenol-lyase (TPL) from Citrobacter freundii is dependent on monovalent cations, K+ or NH4+, for high activity. We have shown previously that Glu-69, which is a ligand... -
Datenkuratierung In Den Sozial- Und Wirtschaftswissenschaften : Qualität Stat...
Die Ziele der Open-Access-Bewegung sind klar umrissen: Alle Ergebnisse öffentlich finanzierter Forschung sollen der Gesellschaft zur Verfügung gestellt werden. Damit Wissen zum... -
r37980778c78--846564b65f52c385ecb3cccfd64a98dc
Protein ADP-ribosyltransferases catalyze the transfer of adenosine diphosphate ribose (ADP-ribose) from nicotinamide adenine dinucleotide (NAD) onto specific target proteins.... -
r37980778c78--abf8e30a95480dae802c80ac51f3c098
Mineral-catalyzed decarboxylation reactions are important in both crude oil formation and, increasingly, biofuel production. In this study we examined decarboxylation reactions... -
Porous Carbon Supports Prepared by Ultrasonic Spray Pyrolysis for Direct Meth...
Carbon powders composed of porous micrometer-sized spheres were synthesized from simple organic salt precursors using ultrasonic spray pyrolysis (USP). These materials were... -
Modulation of T2 Relaxation Time by Light-Induced, Reversible Aggregation of ...
A reversible T2 contrast agent consisting of cross-linked anionic dextran coated iron oxide nanoparticles covalently coupled to a light-sensitive spiropyran (SP)/merocyanine... -
Evaluación del aprendizaje en entornos virtuales y remotos
El webinar “Evaluación del aprendizaje en entornos virtuales y remotos” se impartió el día 23 de junio de 2020 de forma online en el II Ciclo de Capacitaciones por una calidad...
