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Accuracy of genomic selection for grain yield and agronomic traits in soft re...
Abstract Background Genomic selection has the potential to increase genetic gains by using molecular markers as predictors of breeding values of individuals. This study... -
DNetDB: The human disease network database based on dysfunctional regulation ...
Abstract Disease similarity study provides new insights into disease taxonomy, pathogenesis, which plays a guiding role in diagnosis and treatment. The early studies were... -
Millstone: software for multiplex microbial genome analysis and engineering
Abstract Inexpensive DNA sequencing and advances in genome editing have made computational analysis a major rate-limiting step in adaptive laboratory evolution and microbial... -
Downregulation of miR-204 expression defines a highly aggressive subset of Gr...
Abstract Genome-wide expression profiling studies have identified four core molecular subgroups of medulloblastoma: WNT, SHH, Group 3 and Group 4. Molecular markers are... -
Association of Kidney Disease Quality of Life (KDQOL-36) with mortality and h...
Abstract Background For older adults receiving dialysis, health-related quality of life is not often considered in prognostication of death or future hospitalizations. To... -
Association of serum high-density lipoprotein cholesterol with microalbuminur...
Abstract Background The association of serum high-density lipoprotein cholesterol (HDL-C) with microalbuminuria in type 2 diabetes mellitus (T2DM) remains controversial.... -
The French National Registry of patients with Facioscapulohumeral muscular dy...
Abstract Background Facioscapulohumeral muscular dystrophy is a rare inherited neuromuscular disease with an estimated prevalence of 1/20,000 and France therefore harbors about... -
The typically developing paediatric foot: how flat should it be? A systematic...
Abstract Background All typically developing children are born with flexible flat feet, progressively developing a medial longitudinal arch during the first decade of their... -
Allogeneic transplantation of mobilized dental pulp stem cells with the misma...
Abstract Background We recently demonstrated that autologous transplantation of mobilized dental pulp stem cells (MDPSCs) was a safe and efficacious potential therapy for total... -
Gene expression network analyses in response to air pollution exposures in th...
Abstract Background Exposure to air pollution, including traffic-related pollutants, has been associated with a variety of adverse health outcomes, including increased... -
Self-monitoring of health data by patients with a chronic disease: does disea...
Background: There is a growing emphasis on self-monitoring applications that allow patients to measure their own physical health parameters. A prerequisite for achieving... -
Incidence and risk factors for recurrent Henoch-Schönlein purpura in children...
Abstract Background The recurrence rate of Henoch-Schönlein purpura (HSP) is 2.7%–30%, with varied average intervals between the first and second episodes. Few studies have... -
Horizontal gene transfer is not a hallmark of the human genome
Abstract Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as... -
TuberOus SClerosis registry to increase disease Awareness (TOSCA) – baseline ...
Abstract Background Tuberous sclerosis complex (TSC) is a rare autosomal dominant genetic disorder. Many gaps remain in the understanding of TSC because of the complexity in... -
Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome su...
Abstract Background Gout is one of the common inflammatory arthritis which affects many people for inflicting unbearable pain. Macrophage-mediated inflammation plays an... -
Production of human pro-relaxin H2 in the yeast Pichia pastoris
Abstract Background Initially known as the reproductive hormone, relaxin was shown to possess other therapeutically useful properties that include extracellular matrix... -
Development of a silicon limitation inducible expression system for recombina...
Abstract Background An inducible promoter for recombinant protein expression provides substantial benefits because under induction conditions cellular energy and metabolic... -
Loki zupa alleviates inflammatory and fibrotic responses in cigarette smoke i...
Abstract Background Loki zupa formula is kind of a traditional medicines which used to treat airway diseases, especially those caused by abnormal phlegm, such as cough, asthma... -
Production of rosmarinic acid and correlated gene expression in hairy root cu...
Rosmarinic acid (RA) is an active constituent of Ocimum basilicum. It has been shown that hairy root production (measured as dry weight) improves when green basil (O. basilicum... -
Canalization of gene expression is a major signature of regulatory cold adapt...
Abstract Background Transcriptome analysis may provide means to investigate the underlying genetic causes of shared and divergent phenotypes in different populations and help to...
