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Glossogyne tenuifolia (Hsiang-ju) extract suppresses T cell activation by inh...
Abstract Background Glossogyne tenuifolia (GT) (Hsiang-ju) is a Chinese herbal medicine previously exhibited an anti-inflammatory activity. This study aimed to investigate the... -
A case report of intravenous posaconazole in hepatic and renal impairment pat...
Abstract Background Invasive aspergillosis (IA) is a fatal infectious complication among immunocompromised patients. Aspergillus terreus, the fourth common species can be... -
Quorum sensing of Streptococcus mutans is activated by Aggregatibacter actino...
Abstract Background The oral cavity is inhabited by complex microbial communities forming biofilms that can cause caries and periodontitis. Cell-cell communication might play an... -
Proteomics informed by transcriptomics for characterising active transposable...
Abstract Background Aedes aegypti is a vector for the (re-)emerging human pathogens dengue, chikungunya, yellow fever and Zika viruses. Almost half of the Ae. aegypti genome is... -
Differential host gene responses from infection with neurovirulent and partia...
Abstract Background Venezuelan equine encephalitis virus (VEEV) is an alphavirus in the family Togaviridae. VEEV causes a bi-phasic illness in mice where primary replication in... -
The invasome of Salmonella Dublin as revealed by whole genome sequencing
Abstract Background Salmonella enterica serovar Dublin is a zoonotic infection that can be transmitted from cattle to humans through consumption of contaminated milk and milk... -
Point of sampling detection of Zika virus within a multiplexed kit capable of...
Abstract Background Zika, dengue, and chikungunya are three mosquito-borne viruses having overlapping transmission vectors. They cause diseases having similar symptoms in human... -
Characterization of two novel intronic OPA1 mutations resulting in aberrant p...
Abstract Background We report two novel splice region mutations in OPA1 in two unrelated families presenting with autosomal-dominant optic atrophy type 1 (ADOA1) (ADOA or Kjer... -
SYBR green-based one step quantitative real-time polymerase chain reaction as...
Abstract Background The monitoring of vectors is one of the key surveillance measures to assess the risk of arbovirus transmission and the success of control strategies in... -
Identification of nucleoid associated proteins (NAPs) under oxidative stress ...
Abstract Background Bacterial nucleoid consists of genome DNA, RNA, and hundreds of nucleoid-associated proteins (NAPs). Escherichia coli nucleoid is compacted towards the... -
Acute cigarette smoke exposure activates apoptotic and inflammatory programs ...
Abstract Background Smoking and aberrant epithelial responses are risk factors for lung cancer as well as chronic obstructive pulmonary disease and idiopathic pulmonary... -
[6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-st...
Abstract Background [6]-Gingerol, a major component of Zingiber officinale, was previously reported to ameliorate hyperglycemia in type 2 diabetic mice. Endocrine signaling is... -
SLC11A1 polymorphisms and host susceptibility to cutaneous leishmaniasis in P...
Abstract Background The vector-borne cutaneous leishmaniasis (CL) is endemic in several regions of Pakistan mainly affecting poor populations. Host genetic factors, particularly... -
Large intragenic deletion of CDC73 (exons 4–10) in a three-generation hyperpa...
Abstract Background Inactivating mutations of CDC73 cause Hyperparathyroidism-Jaw Tumour syndrome (HPT-JT), Familial Isolated Hyperparathyroidism (FIHP) and sporadic parathyroid... -
Combined use of the Consolidated Framework for Implementation Research (CFIR)...
Abstract Background Over 60 implementation frameworks exist. Using multiple frameworks may help researchers to address multiple study purposes, levels, and degrees of... -
Public health surveillance in the UK revolutionises our understanding of the ...
Abstract Background The ST313 sequence type of Salmonella Typhimurium causes invasive non-typhoidal salmonellosis and was thought to be confined to sub-Saharan Africa. Two... -
Serum low-density lipoprotein and low-density lipoprotein expression level at...
Abstract Background Patients with small-cell lung cancer (SCLC) patients demonstrate varied survival outcomes. Previous studies have reported that lipoproteins are associated... -
Introduction of the DiaGene study: clinical characteristics, pathophysiology ...
Abstract Background Type 2 diabetes is a major healthcare problem. Glucose-, lipid-, and blood pressure-lowering strategies decrease the risk of micro- and macrovascular... -
Maternal blood contamination of collected cord blood can be identified using ...
Abstract Background Cord blood is a commonly used tissue in environmental, genetic, and epigenetic population studies due to its ready availability and potential to inform on a... -
TREatment of ATopic eczema (TREAT) Registry Taskforce: protocol for an intern...
Abstract Background Patients with moderate-to-severe atopic eczema (AE) often require photo- or systemic immunomodulatory therapies to induce disease remission and maintain...
