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Is 1H-MR spectroscopy useful as a diagnostic aid in MSA-C?
Abstract Background Multiple system atrophy (MSA) is a sporadic adult-onset neurodegenerative disease with a cerebellar subtype where ataxic symptoms predominate (MSA-C)... -
Identifying the effect of patient sharing on between-hospital genetic differe...
Abstract Background Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most common healthcare-associated pathogens. To examine the role of inter-hospital patient... -
Polygenic risk for coronary heart disease acts through atherosclerosis in typ...
Abstract Background Type 2 diabetes increases the risk of coronary heart disease (CHD), yet the mechanisms involved remain poorly described. Polygenic risk scores (PRS) provide... -
β-blockers and risk of all-cause mortality in patients with chronic heart fai...
Abstract Background Effects of β-blockers on outcomes in patients with chronic heart failure (CHF) and atrial fibrillation (AF) is still in controversy. Methods Searching was... -
FGF23C-tail improves diabetic nephropathy by attenuating renal fibrosis and i...
Abstract Background High level of serum fibroblast growth factor 23 (FGF23) is implicated in the development and progression of diabetic nephropathy (DN), making it a crucial... -
High-Quality draft genome sequence of the Lotus spp. microsymbiont Mesorhizob...
Abstract Mesorhizobium loti strain CJ3Sym was isolated in 1998 following transfer of the integrative and conjugative element ICEMlSymR7A, also known as the R7A symbiosis island,... -
Identification and validation of a Schistosoma japonicum U6 promoter
Abstract Background RNA polymerase III promoters have been widely used to express short hairpin-RNA (shRNA), microRNA (miRNA), and small guide RNA (sgRNA) in gene functional... -
Allergen immunotherapy for IgE-mediated food allergy: protocol for a systemat...
Abstract Background The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for... -
Complete APTX deletion in a patient with ataxia with oculomotor apraxia type 1
Abstract Background Ataxia with oculomotor apraxia type 1 is an autosomal-recessive neurodegenerative disorder characterized by a childhood onset of slowly progressive... -
Chromosomal integration vectors allowing flexible expression of foreign genes...
Abstract Background Campylobacter jejuni is a major cause of human gastroenteritis yet there is limited knowledge of how disease is caused. Molecular genetic approaches are... -
Development and validation of a novel PCR-RFLP based method for the detection...
Abstract Background Leber’s Hereditary Optic Neuropathy (LHON; MIM 535000) is one of the most commonly inherited optic neuropathies and it results in significant visual... -
The effect of polymyxin B hemoperfusion on modulation of human leukocyte anti...
Abstract Background Recent randomized trials have not found that polymyxin B hemoperfusion (PMX-HP) improves outcomes for patients with sepsis. However, it remains unclear... -
Correction to: DNA copy number evolution in Drosophila cell lines
Following publication of the original article [1], the authors reported the following errors. -
Effectiveness of spiritual care training to enhance spiritual health and spir...
Abstract Background Although spiritual care is a basic element of holistic nursing, nurses’ spiritual care knowledge and abilities are often unable to satisfy patients’... -
Contribution of a synchronic teleneurology program to decrease the patient nu...
Abstract Backround There is a shortage of medical specialists in Chile, including neurologists; currently, there are 56,614 patients waiting for a first adult Neurology... -
Skin microbiota analysis-inspired development of novel anti-infectives
Abstract Background The alarming spread of antimicrobial resistance requires the development of novel anti-infective drugs. Despite the recent research focus on the human... -
Bone marrow mesenchymal stromal cells attenuate silica-induced pulmonary fibr...
Abstract Background Pulmonary fibrosis induced by silica dust is an irreversible, chronic, and fibroproliferative lung disease with no effective treatment at present. Previous... -
Physicians’ professional autonomy and their organizational identification wit...
Abstract Background Managing medical professionals is challenging because professionals tend to adhere to a set of professional norms and enjoy autonomy from supervision. The... -
MEN1 redefined, a clinical comparison of mutation-positive and mutation-negat...
Abstract Background Multiple Endocrine Neoplasia type 1 (MEN1) is diagnosed when two out of the three primary MEN1-associated endocrine tumors occur in a patient. Up to 10–30 %... -
Effect of a short course of iron polymaltose on acquisition of malarial paras...
Abstract Background Concern exists about the safety of iron supplementation given to individuals in malarious areas. The possible unfavourable impact of iron supplementation on...
