We present a quantum mechanical/molecular mechanical (QM/MM) study using the AM1 Hamiltonian and a flexible MM part on the mode of action of the bovine lens leucine...

Hemolytic activity against horse erythrocytes, calculated hydrophobicity, hydrophobic moment and net charge of Cap18 and Cap18 derivatives.

We present a quantum mechanical/molecular mechanical (QM/MM) study using the AM1 Hamiltonian and a flexible MM part on the mode of action of the bovine lens leucine...

To investigate diazepinone analogues as γ-turn mimics, seven 1,4-benzodiazepin-2-ones 6 and fourteen pyrrolo­[1,2-d]­[1,4]­benzodiazepin-6-ones 4 and 5 were synthesized from...

To investigate diazepinone analogues as γ-turn mimics, seven 1,4-benzodiazepin-2-ones 6 and fourteen pyrrolo­[1,2-d]­[1,4]­benzodiazepin-6-ones 4 and 5 were synthesized from...

We present a quantum mechanical/molecular mechanical (QM/MM) study using the AM1 Hamiltonian and a flexible MM part on the mode of action of the bovine lens leucine...

Due to the rapid emergence of resistance to classical antibiotics, novel antimicrobial compounds are needed. It is desirable to selectively kill pathogenic bacteria without...

Results of XRD analyses on residues from Porc-Epic Cave's ochre processing tools and ochre-stained artefacts.

1Statistics for data from the highest-resolution shell are shown in parentheses. 2 R sym =(ΣΣ|Ihkl−〈I〉|)/(ΣIhkl), where the average intensity <I> is taken...

Antimicrobial activity of Cap18 and selected antibiotics.

Aquaculture is a growing industry, increasing the need for understanding host–pathogen interactions in fish. The skin and mucosal surfaces, covered by a mucus layer composed of...

Oligomers of α-aminoisobutyric acid (Aib) are achiral peptides that typically adopt 310 helical conformations in which enantiomeric left- and right-handed conformers are,...

aSequences in upper case letters are derived from the genome sequences of H. pylori 26695 [25], H. hepaticus[32], C. jejuni[33] and W. succinogenes[34]. Sequences introduced for...

Descriptive statistics for the control beliefs indicating how likely using antibiotics prudently will, or how the following factors will create ease of using antibiotics prudently.

We present a quantum mechanical/molecular mechanical (QM/MM) study using the AM1 Hamiltonian and a flexible MM part on the mode of action of the bovine lens leucine...

Half-lives and first-order equations of imazapic in response to different factors.

Unfavorable amino acid substitutions of Cap18 leading to increased hemolytic activity against horse erythrocytes.

The glycolytic enzyme enolase catalyzes the reversible elimination of water from 2-phosphoglycerate (2-PGA) to form phosphoenolpyruvate (PEP). Two magnesium ions in the active...

Gaegurin 5 is a 24-residue, membrane-active antimicrobial peptide isolated from the skin of an Asian frog, Rana rugosa. We recently reported the antimicrobial activities of two...

Cu, ZnSOD, a ubiquitous antioxidant enzyme present in the cytosol, nucleus, peroxisomes and mitochondrial intermembrane space of eukaryotic cells, protects against superoxide...