CAN is a good reagent for the transformation of 2-hydroxyethyl ether units to alcohols. Significantly, many functional groups can tolerate the reaction conditions, although they...

Cyclic mixed acetals with pendant diazoketone side chains undergo efficient rearrangement to ether-bridged cyclooctanoid systems upon treatment with Cu(hfacac)2. This result...

The synthesis of new β,β-difluorinated cyclic quaternary α-amino acid derivatives 1 in which a ring-closing metathesis reaction (RCM) constitutes the key step is described. The...

The CpFe+ group activates the perallylation of the benzylic groups of arenes using KOH and allylbromide under ambient conditions. This reaction can be followed by...

The total synthesis of the diterpene kellermanoldione 1 is reported. Stepwise [4 + 2] cycloaddition of the ketal diene 8 and the allenoate 3 afforded the exo adduct 10x as the...

In fluorous triphasic reactions, such as bromination of alkenes by dibromine and dealkylation of aromatic ethers by boron tribromide, the middle fluorous phase acts as a liquid...

A stereoselective halo-etherification of chiral enamides is described here. This work provides an approach to halogen containing cyclic ethers and reveals further mechanistic...

The tribological properties of the molecularly thin films of asymmetric ether (1,3-dimethylbutyl octyl ether, AE) and fluorinated asymmetric ether...

The electron-transfer photochemistry of homochrysanthemol, 1, resulted exclusively in intramolecular “substitution” at the quaternary cyclopropane carbon, generating the...

The lithiation reaction of cis- and trans-N-alkyl-2,3-diphenylaziridines has been investigated. While cis-diphenylaziridines do not undergo any lithiation upon treatment with...

Synthesis of a Novel Poly(binaphthylene ether) Containing Trifluoromethyl Groups with a Low Dielectric Constant

Diisopropylsilyl bis-enol ethers are shown to be powerful intermediates for the diastereoselective dimerization and cross-coupling of cyclic ketones. The trends observed for the...

A wide spectrum of alcohols and phenols are readily transformed to the corresponding 2-tetrahydrofuranyl ethers in good to excellent yields using CrCl2 and CCl4 in THF under...

A convergent total synthesis of leptofuranin D is described. The linear polyketide C12−C24 segment was assembled through addition of a chiral allenylzinc reagent, derived from...

A new set of orthogonal protecting groups has been developed based on the use of a diethylisopropylsilyl (DEIPS), methylnaphthyl (Nap), allyl ether, and levulinoyl (Lev) ester....

A new diphenyl ether (1), along with 12 known compounds, was isolated from the lichen Diploicia canescens. The structure of compound 1 was elucidated by spectroscopic data...

Heteroaryl Substituted Polythiophenes:  Chemical and Electrochemical Syntheses and Characterization of Poly[3-(9-tris(ethylene glycol) monomethyl ether)carbazoylthiophene]

Borane-mediated reduction of aryl and alkyl ketones with α-aryl- and α-pyridyloxy groups affords β-hydroxy ethers in high enantiomeric purity (up to 99% ee) and in good yield,...

The rhodium-catalyzed carbonylative [3+2+1] cycloaddition of trienes into bicyclohexenones has been developed. The carbonylated cycloaddition products have a high...

Diastereoselective [2 + 2] cyclizations of aldehyde- and ketone-derived silyl enol ethers with acrylates is described. The use of the tris(trimethylsilyl)silyl group allows for...