Rating codes: N, DSEI not addressed; I, DSEI implicitly addressed; E, DSEI explicitly addressed; R, DSEI explicitly addressed with recommendations.

Financial and academic COIs and roles of committee members. (XLSX 30 kb)

Additional file 2. This file includes all the references screened in the systematic review and the reason for exclusion.

aThe French language guideline “Diagnostic et prise en charge de la maladie d'Alzheimer et des maladies apparentées” consists of 40 pages but contains the same ten chapters as...

Spreadsheet Self-perception and knowledge of EBM. (XLSX 87 kb)

Background There are a few studies of alignment between different knowledge-indices for evidence-based medicine (EBM). The aim of this study was to investigate whether the type...

Background Feline herpesvirus 1 is a highly contagious virus that affects many cats. Virus infection presents with flu-like signs and irritation of ocular and nasal regions....

The purpose of this paper is to describe a patient engagement event designed to create an educational workbook with smokers who drink alcohol at harmful levels. The goal was to...

Background (Semi-)systematic approaches to finding, analysing, and synthesising ethics literature on medical topics are still in their infancy. However, our recent systematic...

Background Overviews of reviews (overviews) compile data from multiple systematic reviews to provide a single synthesis of relevant evidence for decision-making. Despite their...

Background The decision to conduct a randomized controlled trial (RCT) in a field raises ethical as well as scientific issues. From the clinical equipoise literature, future...

Background Women with breast cancer want to participate in treatment decision-making. Guidelines have confirmed the right of informed shared decision-making. However, previous...

Background The influence, legitimacy and application of Evidence Based Medicine (EBM) in the world is growing as a tool that integrates, the best available evidence to decision...

Background Provider misconceptions and biases about contraceptive methods are major barriers to family planning access for women in low- and middle-income countries, including...

Background The uptake and use of clinical guidelines is often insufficient to change clinical behaviour and reduce variation in practice. As a consequence of diverse...

Background Medical devices play an important role in the diagnosis, prevention, treatment and care of diseases. However, compared to pharmaceuticals, there is no rigorous formal...

Intervention slides, copy of the intervention slides that were embedded into our simulation research study. (PPTX 66 kb)

Background and purpose The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set of clinical practice...

Abstract Background Evidence-based clinical research poses special barriers in the field of nutrition. The present review summarises the main barriers to research in the field...

Abstract Background Expert psychiatrists conducting work disability evaluations often disagree on work capacity (WC) when assessing the same patient. More structured and...