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Perioperative surgery- and anaesthesia-related risks of laparoscopic Roux-en-...
Abstract Background Conservative obesity treatment often leads to limited results. Bariatric surgery is highly efficient, but the candidates are at risk of developing... -
The potassium channel KCa3.1 represents a valid pharmacological target for mi...
Abstract Background Recent studies described a critical role for microglia in Parkinson’s disease (PD), where these central nerve system resident immune cells participate in the... -
iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated d...
Abstract Background Previous research indicated that nitric oxide synthase (NOS) is the key molecule for S-nitrosylation of ryanodine receptor 1 (RyR1) in DMD model mice (mdx... -
Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in p...
Abstract Background Transient receptor potential ankyrin 1 (TRPA1) is a membrane-associated cation channel, widely expressed in neuronal cells and involved in nociception and... -
In vivo evidence for the contribution of peripheral circulating inflammatory ...
Abstract Background Neuroinflammation is implicated in the development and progression of many neurodegenerative diseases. Conditions that lead to a peripheral immune response... -
An exploration of the experiences of GP registrar supervisors in small rural ...
Abstract Background In Australia registrar training to become a general practitioner (GP) involves three to four years of supervised learning with at least 50% of GP registrars... -
Prevention of multiple system atrophy using human bone marrow-derived mesench...
Abstract Background Multiple system atrophy (MSA) is a sporadic neurodegenerative disorder of unknown etiology, but is closely associated with damage to dopaminergic neurons.... -
Tonic ATP-mediated growth suppression in peripheral nerve glia requires arres...
Abstract Normal Schwann cells (SCs) are quiescent in adult nerves, when ATP is released from the nerve in an activity dependent manner. We find that suppressing nerve activity... -
Influence of menstrual cycle phase on resting-state functional connectivity i...
Abstract Background Sex differences in tobacco-related morbidity and mortality exist, with women experiencing more severe health consequences and greater difficulty with smoking... -
Origin of third harmonic generation in plasmonic nanoantennas
Plasmonic nanoantennas have been recently proposed to boost nonlinear optical processes. In a metal dipole nanoantenna with a dielectric nanoparticle placed in the gap, the... -
Real-time handheld multispectral optoacoustic imaging
Multispectral optoacoustic tomography (MSOT) of functional and molecular contrast has the potential to find broad deployment in clinical practice. We have developed the first... -
Expression of ACE2 and a viral virulence-regulating factor CCN family member ...
Abstract It has been reported that coronavirus disease 2019 (COVID-19) causes not only pneumonia but also systemic inflammations including central nervous system (CNS)... -
Exploring differences in the use of the statin choice decision aid and diabet...
Abstract Background Shared decision making is essential to patient centered care, but can be difficult for busy clinicians to implement into practice. Tools have been developed... -
Do Cochrane summaries help student midwives understand the findings of Cochra...
Abstract Background Abstracts and plain language summaries (PLS) are often the first, and sometimes the only, point of contact between readers and systematic reviews. It is... -
Efficacy of acupuncture in the prevention and treatment of chemotherapy-induc...
Abstract Background Chemotherapy-induced nausea and vomiting (CINV) is a common and distressing side effect. We conducted this clinical trial to compare the effectiveness of... -
AMPK-dependent and independent actions of P2X7 in regulation of mitochondrial...
Abstract Background P2X7 is ubiquitously expressed in myeloid cells and regulates the pathophysiology of inflammatory diseases. Since mitochondrial function in microglia is... -
Non-pungent long chain capsaicin-analogs arvanil and olvanil display better a...
The nutritional compound capsaicin inhibits the invasion of many types of human cancers. The clinical development of capsaicin as an anti-cancer drug is limited due to its... -
Exploring physiological signals on people with Duchenne muscular dystrophy fo...
Abstract Background Arm support devices are available to support people with Duchenne muscular dystrophy (DMD), but active trunk support devices are lacking. An active trunk... -
Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye dr...
Abstract Background To determine the effect of various factors to the preservation rate of the conjunctival layer borderlines of glaucomatous eyes treated with anti-glaucoma eye... -
Co-activator candidate interactions for orphan nuclear receptor NR2E1
Abstract Background NR2E1 (Tlx) is an orphan nuclear receptor that regulates the maintenance and self-renewal of neural stem cells, and promotes tumourigenesis. Nr2e1-null mice...
