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A systematic review of the relationship between subchondral bone features, pa...
Abstract Introduction Bone is an integral part of the osteoarthritis (OA) process. We conducted a systematic literature review in order to understand the relationship between... -
Walking with a powered ankle-foot orthosis: the effects of actuation timing a...
Abstract Background In the last decades, several powered ankle-foot orthoses have been developed to assist the ankle joint of their users during walking. Recent studies have... -
Quantitative evaluation of corneal epithelial edema after cataract surgery us...
Abstract Purpose The optical density of the cornea can be evaluated quantitatively by “densitometry” using a rotating Scheimpflug camera. Densitometry allows evaluation of... -
Identification of plasma microRNA expression changes in multiple system atrop...
Abstract MicroRNAs (miRNAs) are endogenous small (18–25 nt), single-stranded, non-coding RNAs that play key roles in post-transcriptional gene expression regulation. The... -
Role of tyramine in calcium dynamics of GABAergic neurons and escape behavior...
Abstract Background Tyramine, known as a â trace amineâ in mammals, modulates a wide range of behavior in invertebrates; however, the underlying cellular and circuit... -
Could patents interfere with the development of a cardiovascular polypill?
Abstract Background The Wellcome Trust, the World Health Organization, and cardiologists have advocated for the idea of a “polypill” containing multiple cardiovascular drugs to... -
Association of four imprinting disorders and ART
Abstract Background Human-assisted reproductive technologies (ART) are a widely accepted treatment for infertile couples. At the same time, many studies have suggested the... -
Non-technical skills evaluation in the critical care air ambulance environmen...
Abstract Background In the isolated and dynamic health-care setting of critical care air ambulance transport, the quality of clinical care is strongly influenced by... -
Chronic wide-field imaging of brain hemodynamics in behaving animals
Chronically monitoring cerebral activities in awake and freely moving status is very important in physiological and pathological studies. We present a novel standalone... -
The cylindromatosis (CYLD) gene and head and neck tumorigenesis
Abstract Germline CYLD mutation is associated with the development of a rare inheritable syndrome, called the CYLD cutaneous syndrome. Patients with this syndrome are distinctly... -
Finite element analysis of cementless femoral stems based on mid- and long-te...
Abstract Background Femoral bone remodeling in response to stress shielding induces periprosthetic bone loss. Computerized finite element analysis (FEA) is employed to... -
pH-mediated upregulation of AQP1 gene expression through the Spi-B transcript...
Abstract Background Bicarbonate-based peritoneal dialysis (PD) fluids enhance the migratory capacity and damage-repair ability of human peritoneal mesothelial cells by... -
Repetitive element hypermethylation in multiple sclerosis patients
Abstract Background Multiple sclerosis (MS) is a complex disorder of the central nervous system whose cause is currently unknown. Evidence is increasing that DNA methylation... -
Co-targeting of EGFR by co-expressed miRNA-193a-3p/−5p in lung cancer
Abstract MicroRNAs (miRNAs) function as important oncogenes or tumor suppressors in each stage of cancer development. While previous studies focused on the individual miRNA and... -
The use of empirical research in bioethics: a survey of researchers in twelve...
Abstract Background The use of empirical research methods in bioethics has been increasing in the last decades. It has resulted in discussions about the ‘empirical turn of... -
High expression of Linc00959 predicts poor prognosis in breast cancer
Abstract Background Accumulating studies have focused on the oncogenic roles of the newly identified lncRNAs in human cancers. The aim of this study was to examine the... -
Extracorporeal membrane oxygenation for life-threatening asthma refractory to...
Abstract Background The use of extracorporeal membrane oxygenation (ECMO) in cases of near-fatal asthma (NFA) has increased, but the benefits and potential complications of this... -
T-ARMS PCR genotyping of SNP rs445709131 using thermostable strand displaceme...
Abstract Objectives In a recent publication, we reported the successful use of tetra primer-amplification refractory mutation system based polymerase chain reaction (T-ARMS-PCR)... -
Galectin-1 from cancer-associated fibroblasts induces epithelial–mesenchymal ...
Abstract Background Gastric cancer (GC) is characterized by the excessive deposition of extracellular matrix, which is thought to contribute to this tumor’s malignant behavior.... -
The course of diaphragm atrophy in ventilated patients assessed with ultrasou...
Abstract Introduction Mechanical ventilation and the effect of respiratory muscle unloading on the diaphragm cause ventilator-induced diaphragmatic dysfunction (VIDD). Atrophy...