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Defining the clinical pathway in cochrane diagnostic test accuracy reviews
Abstract Background The value of a medical test depends on the context in which it might be used. Ideally, questions, results and conclusions of a diagnostic test accuracy (DTA)... -
Vasoresponsiveness in patients with heart failure (VASOR): protocol for a pro...
Abstract Background Vasoplegia is a severe complication which may occur after cardiac surgery, particularly in patients with heart failure. It is a result of activation of... -
Screening value of the Center for epidemiologic studies – depression scale am...
Abstract Background Depression is believed to be under-diagnosed and under-treated in people living with HIV/AIDS (PLHIV). Early screening and referral to mental health services... -
A twenty-four-hour observational study of hand hygiene compliance among healt...
Abstract Background Hand hygiene (HH) is recognized as the single most effective strategy for preventing health care–associated infections. In developing countries, data on hand... -
At what times during infection is SARS-CoV-2 detectable and no longer detecta...
Abstract Background Tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral ribonucleic acid (RNA) using reverse transcription polymerase chain reaction... -
Improving empathy and self-efficacy in caregivers of persons with intellectua...
Abstract Background A secure attachment with one or more caregivers is one of the most important predictors of cognitive development and emotional wellbeing. Persons with... -
Contemporary women prisoners health experiences, unique prison health care ne...
Abstract Background Sub Saharan African (SSA) prisons have seen a substantial increase in women prisoners in recent years. Despite this increase, women prisoners constitute a... -
Real world experience of patients with amyotrophic lateral sclerosis (ALS) in...
Background: Treatment of spasticity poses a major challenge in amyotrophic lateral sclerosis (ALS) patient management. Delta-9-tetrahydrocannabinol (THC):cannabidiol (CBD)... -
Combination of Ranibizumab with macular laser for macular edema secondary to ...
Abstract Background It is not clear whether macular laser combined with anti-vascular endothelial growth factor (VEGF) can reduce the number of anti-VEGF injections in the... -
‘You are Okay’: a support and educational program for children with mild inte...
Abstract Background Children of parents with a mental illness or substance use disorder (COPMI) have an increased risk of developing social-emotional problems themselves. Fear... -
Neuronal impairment following chronic Toxoplasma gondii infection is aggravat...
Abstract Background It has become increasingly evident that the immune and nervous systems are closely intertwined, relying on one another during regular homeostatic conditions.... -
Preventing sexual violence in college men: a randomized-controlled trial of G...
Abstract Background Sexual violence—any sexual act committed against a person without freely given consent—disproportionately affects women. Women’s first experiences of sexual... -
Buying and selling human eggs: infertility providers’ ethical and other conce...
Abstract Background Egg donor agencies are increasingly being used as part of IVF in the US, but are essentially unregulated, posing critical ethical and policy questions... -
Role of tyramine in calcium dynamics of GABAergic neurons and escape behavior...
Abstract Background Tyramine, known as a â trace amineâ in mammals, modulates a wide range of behavior in invertebrates; however, the underlying cellular and circuit... -
Scopolamine augmentation of a newly initiated escitalopram treatment for majo...
Abstract Background Major depressive disorder (MDD) is a prevalent and disabling disorder that can lead to heavy individual, familial, and societal burdens. Although... -
HIV testing and counselling experiences: a qualitative study of older adults ...
Abstract Background Finding HIV infected persons and engaging them in care is crucial in achieving UNAIDS 90–90-90 targets; diagnosing 90% of those infected with HIV, initiating... -
Physical inactivity, gender and culture in Arab countries: a systematic asses...
Abstract Background Physical inactivity is associated with excess weight and adverse health outcomes. We synthesize the evidence on physical inactivity and its social... -
Relationship between age and bronchodilator response at diagnosis in adult-on...
Abstract Background Possible variation in bronchodilator response (BDR) according to age at the diagnosis of adult-onset asthma is unknown. Our aim was to assess if BDR in FEV1... -
Physical and psychosomatic health outcomes in people bereaved by suicide comp...
Abstract Background Little research has been conducted into the physical health implications of suicide bereavement compared to other causes of death. There is some evidence... -
Assessment and improvement of HIV screening rates in a Midwest primary care p...
Abstract Background Universal human immunodeficiency virus (HIV) screening remains low in many clinical practices despite published guidelines recommending screening for all...