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Hypotensive activity of <i>Campomanesia xanthocarpa</i> leaf extract: beyond ...
The ability of Campomanesia xanthocarpa leaf extract (CXLE) to alter blood pressure and heart rate was evaluated in anesthetized rats. The CXLE-induced hypotension was evaluated... -
Identification of a Novel, Selective GABA<sub>A</sub> α5 Receptor Inverse Ago...
In pursuit of a GABAA α5-subtype-selective inverse agonist to enhance cognition, a series of 6,7-dihydro-2-benzothiophen-4(5H)-ones has been identified as a novel class of GABAA... -
Half-Sandwich Group 4 Metal Siloxy and Silsesquioxane Complexes: Soluble Mod...
The cuboctameric hydroxysilsesquioxane (c-C5H9)7Si8O12(OH) (2), obtained after hydrolysis of (c-C5H9)7Si8O12Cl (1), and triphenylsilanol have been applied as model supports for... -
Flavonoids Possess Neuroprotective Effects on Cultured Pheochromocytoma PC12 ...
Despite the classical hormonal effect, estrogen possesses a neuroprotective effect in the brain, which has led many to search for novel treatments for neurodegenerative... -
Additional file 2 of iNOS is not responsible for RyR1 S-nitrosylation in mdx ...
Additional file 2. The original full blot of iNOS for both tibialis anterior and diaphragm muscle. (A) Whole image of PVDF membrane of Fig. 3b (iNOS expression in TA muscle) and... -
dedup_wf_001--d587f02a94e0a86571a473ab130947b6
Additional file 2. Distribution of p-PERK+ and p-eIF2α + neurons relative to beta-amyloid plaques in the AON. Immunohistochemistry for p-IRE1α and CK1δ in the AON and CA1 region. -
De Novo Design of a Novel Oxazolidinone Analogue as a Potent and Selective α<...
De Novo Design of a Novel Oxazolidinone Analogue as a Potent and Selective α1A Adrenergic Receptor Antagonist with High Oral Bioavailability -
r37980778c78--9f14fac0dd0317809458d7cf8d1490ae
In this study, we have developed a two receptor model system to describe the R and R* states of G-protein coupled receptors, specifically the alpha1D adrenergic receptor. The... -
Gap junctions amplify TRPV4 activation-initiated cell injury via modification...
The elevated intracellular Ca2+ and oxidative stress are well-reported mechanisms behind renal tubular epithelial injury initiated by various insults. Given that TRPV4 and... -
Additional file 1 of Stimulator of IFN genes mediates neuroinflammatory injur...
Additional file 1: Supplementary Table S1. Information of primers used for RT-PCR. -
Role of Proteolysis in Caspase-8 Activation and Stabilization<sup>†</sup>
Caspase-8 is an apoptotic protease that is activated at the cytosolic face of the cell membrane. Activation relies on adaptor-induced dimerization of monomeric caspase-8 and is... -
Additional file 3: of Towards a scientific interpretation of the terroir conc...
Heat map representing the areas of the main chromatographic peaks assessed by HPLC-DAD and HPLC-ESI-MS for the seven vineyards and fully-ripened berries. Each value represents... -
r37980778c78--c546ab278bf95008858d42d1728be021
One-electron oxidation of [(Me3Si)2N]2VX(THF) (X = Cl, Me, Ph) with CuCl afforded the V(IV), d1 species [(Me3Si)2N]2VCl(X) in moderate yields after crystallization from... -
Bicyclo[2.2.1]heptane and 6,6-Dimethylbicyclo[3.1.1]heptane Derivatives: Ora...
Bicyclo[2.2.1]heptane and 6,6-Dimethylbicyclo[3.1.1]heptane Derivatives: Orally Active, Potent, and Selective Prostaglandin D2 Receptor Antagonists -
Die Regulation der Pyruvatdecarboxylasen aus den Schlauchpilzen Kluyveromyces...
Doktorarbeit Biochemie: Die Regulation der Pyruvatdecarboxylasen aus den Schlauchpilzen Kluyveromyces lactis, Saccharomyces cerevisiae und Neurospora crassa PhD thesis... -
dedup_wf_001--0cbf0a6674eba5a6c433a01c92f9057e
Παρουσίαση στο συμπόσιο "Ανοικτή Επιστήμη στον ελληνικό ερευνητικό ιστό: Ερευνητικές Διαδικασίες, Ερευνητικά Δεδομένα, Συνεργασίες" που διοργάνωσε το Ερευνητικό Κέντρο “Αθηνά”,...