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High frequency of pre-existing neutralizing antibody responses in patients wi...
Abstract Background This study aims to identify dengue neutralizing antibody response in patients with dengue from a well-characterized cohort during an outbreak in central... -
How acceptable is it for HIV positive African, Caribbean and Black women to p...
Abstract Background The African, Caribbean and Black communities have been found to be reluctant to participate in health research in North America. This is partly attributed to... -
Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caen...
Abstract Background Many pathogens secrete toxins that target key host processes resulting in the activation of immune pathways. The secreted Pseudomonas aeruginosa toxin... -
Dimerized translationally controlled tumor protein increases interleukin-8 ex...
Abstract Background Histamine releasing factor (HRF) is a unique cytokine known to regulate a variety of immune cells in late allergic reactions. In the previous study, we... -
A randomised, placebo-controlled trial of anti–interleukin-1 receptor 1 monoc...
Abstract Background Interleukin-1 receptor 1 (IL-1R1) inhibition is a potential strategy for treating patients with chronic obstructive pulmonary disease (COPD). MEDI8968, a... -
Combined effect of BCG vaccination and enriched environment promote neurogene...
Abstract Background The spatial learning abilities of developing mice benefit from extrinsic cues, such as an enriched environment, with concomitant enhancement in cognitive... -
NLRP3 inflammasome activation in murine macrophages caused by Neospora caninu...
Abstract Background Neospora caninum is an intracellular parasite that causes significant economic losses in cattle industry. Understanding the host resistance mechanisms in the... -
Prescription of antibiotics to children with acute otitis media in Danish gen...
Abstract Background Acute otitis media (AOM) is a common and most often self-limiting infection in childhood, usually managed in general practice. Even though antibiotics are... -
Comparative analysis of the root transcriptomes of cultivated and wild rice v...
Abstract Background Magnaporthe oryzae, the causal fungus of rice blast disease, negatively impacts global rice production. Wild rice (Oryza rufipogon), a relative of cultivated... -
Transcriptional regulation of stilbene synthases in grapevine germplasm diffe...
Abstract Background To limit the impact of the downy mildew disease of grapevine and reduce the need to recur to chemical treatments, an effective strategy might be recovering... -
Toxicity responses of Cu and Cd: the involvement of miRNAs and the transcript...
Abstract Background MicroRNAs are important posttranscriptional regulators of gene expression playing a role in developmental processes as well as in stress responses, including... -
Noninvasive ventilation for severely acidotic patients in respiratory interme...
Abstract Background Severe acidosis can cause noninvasive ventilation (NIV) failure in chronic obstructive pulmonary disease (COPD) patients with acute hypercapnic respiratory... -
The pope and the pill: sex, catholicism and women in post-war England
The pope and the pill: sex, catholicism and women in post-war England -
Duration of antibiotic therapy in critically ill patients: a randomized contr...
Abstract Background The rational use of antibiotics is one of the main strategies to limit the development of bacterial resistance. We therefore sought to evaluate the... -
The effects of daily fasting hours on shaping gut microbiota in mice
Abstract Background It has recently been reported that intermittent fasting shapes the gut microbiota to benefit health, but this effect may be influenced to the exact fasting... -
Microglial depletion and repopulation in brain slice culture normalizes sensi...
Abstract Background Microglia are critical mediators of neuroimmune pathology across multiple neurologic disorders. Microglia can be persistently activated or “primed” by...
