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r37980778c78--088172a2a7cda9b5bc4673bb862e5a4a
From the roots of Lespedeza cyrtobotrya, 45 flavonoids were isolated along with 20 new and 25 known compounds. Lipophilic flavonoids 2, 3, 7, 9, 11, 28, 30, and 39 exhibited... -
Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,...
Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to eliminate potential in vivo hydrolysis to a... -
Development of a Novel Self-Microemulsifying Drug Delivery System for Reducin...
The development of HIV protease inhibitors (PIs) has been one of the most significant advances of the past decade in controlling HIV infection. Unfortunately, the benefits of... -
Catalytic Carbon−Halogen Bond Activation: Trends in Reactivity, Selectivity,...
We have theoretically studied the oxidative addition of all halomethanes CH3X (with X = F, Cl, Br, I, At) to Pd and PdCl-, using both nonrelativistic and... -
r37980778c78--f5680ee4bfad1708193c9c95ea6978c9
Ultrafast 2D HMBC spectroscopy permits real-time monitoring of a reaction based on the structural changes produced in a carbonyl carbon atom. This new technique was used to... -
r37980778c78--20d5cb9ef2131f7c2f5fd1f5ab7c3f3a
The development of n-pentenyl furanosyl donors has been tested using arabinose as a model. The readily prepared ortho ester (NPOE) is converted into disarmed (NPGAC) and thence... -
r37980778c78--308e0d829603d8f8f45ed47c2eb7a3bc
Exposure to diesel exhaust (DE) has been associated with acute cardiopulmonary and vascular responses, chronic noncancer health effects, and respiratory cancers in humans. To... -
Ruthenium-Catalyzed [2 + 2] Cycloadditions of Bicyclic Alkenes with Alkynyl P...
Ruthenium-catalyzed [2 + 2] cycloadditions of bicyclic alkenes with alkynyl phosphonates were investigated. The phosphonate moieties were found to be compatible with the... -
Discovery of Potent 3,5-Diphenyl-1,2,4-oxadiazole Sphingosine-1-phosphate-1 (...
A class of 3,5-diphenyl-1,2,4-oxadiazole based compounds have been identified as potent sphingosine-1-phosphate-1 (S1P1) receptor agonists with minimal affinity for the S1P2 and... -
Design and Synthesis of Potent Cystine-Free Cyclic Hexapeptide Agonists at th...
Cyclic hexapeptides, incorporating a dipeptide unit in place of the disulfide bond found in urotensin, were prepared and screened at the human urotensin receptor. The bridging... -
Anhydrolide Macrolides. 1. Synthesis and Antibacterial Activity of 2,3-Anhydr...
A series of 3-descladinosyl-2,3-anhydro-6-O-methylerythromycin A 11,12-carbamate analogues have been synthesized and evaluated for antibacterial activity. These compounds were... -
Metal−Metal Multiple Bonds in Early/Late Heterobimetallics Support Unusual Tr...
Reduction of Zr/Co heterobimetallic complexes ICo(MesNPiPr2)3ZrCl (1) and ICo(iPrNPiPr2)3ZrCl (2) with excess Na/Hg under N2, followed by subsequent benzene extraction to remove... -
Efficient Synthesis of MUC4 Sialylglycopeptide through the New Sialylation Us...
Sialylation reactions using a new sialyl donor, diethyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-β-d-glycero-d-galacto-2-nonulopyranosylonamide phosphite... -
r37980778c78--171b2989a7b99d872f8aab415bba7cb6
A new and promising group of antibacterial agents, collectively known as the oxazolidinones and exemplified by linezolid (PNU-100766, marketed as Zyvox), have recently emerged... -
r37980778c78--dc669ea7dab313dcdfbab5d71f789ca6
The polyfluorination of α-(arylthio)carbonyl compounds was achieved by a successive application of polyfluorination using IF5, Friedel−Crafts arylation, and desulfurizing... -
Ventajas del formato ePub para la difusión de contenidos en Humanidades: just...
Una versión en pdf del contenido está disponible en https://doi.org/10.5281/zenodo.2580057 -
Open Access Für Forschungsergebnisse. Forschungsdatenmanagement In Der Praxis
Open Access für Forschungsergebnisse: Forschungsdatenmanagement in der Praxis Die Technische Universität Berlin unterstützt den offenen Zugang zu Forschungsdaten und... -
A Ti<sub>2</sub>Ru<sub>2</sub>Pd<sub>2</sub> Oxo−Sulfido Cluster Synthesized ...
A Ti2Ru2Pd2 Oxo−Sulfido Cluster Synthesized by Linking Two Rationally Preorganized TiRuPdS2 Heterotrimetallic Units with an Oxo Ligand: Its Reaction with an Alkyne -
Reactivity of Aluminum Cluster Anions with Water: Origins of Reactivity and M...
The reactivity of aluminum anion clusters with water was found to exhibit variations with size, with some clusters exhibiting negligible reactivity, others absorbing one or more... -
Sensitive and Convenient Yeast Reporter Assay for High-Throughput Analysis by...
The yeast reporter assay has been widely used in various applications such as detection of endocrine disruptors and analysis of protein−protein interactions by the yeast...
